Which Should You Choose: Generic Orlistat or Xenical?
Orlistat vs Xenical: Identical Clinical Effects
The most important fact when comparing orlistat and Xenical is that they contain exactly the same active ingredient at identical strength. Both deliver 120mg orlistat per capsule, working through the same mechanism to block approximately one third of dietary fat absorption. Neither medication causes weight gain when used correctly alongside a reduced-calorie, lower-fat diet. Clinical effectiveness is equivalent between generic orlistat 120mg and branded Xenical 120mg.
Price Comparison: Significant Savings with Generic Orlistat
Generic orlistat offers substantial cost savings compared to branded Xenical. A 4-week supply (84 capsules) costs £29.69 for orlistat versus £38.69 for Xenical with EDM10 discount - saving £9 per month. Over 12 weeks, you save £29.70 choosing generic orlistat at £86.39 compared to Xenical at £116.09. Both options include prescription and next-day delivery from our GPhC-registered Leicester pharmacy.
Why Neither Orlistat Nor Xenical Cause Weight Gain
Concerns about orlistat causing weight gain are unfounded when the medication is used correctly. Orlistat works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, reducing calorie intake from dietary sources. Weight gain may occur if you discontinue treatment and return to previous eating patterns, or if dietary guidelines aren't followed properly.
Alli 60mg: Lower-Strength Alternative
For those preferring a gentler starting point, Alli 60mg offers half the dose of prescription-strength orlistat. At £26.09 for 4 weeks with EDM10, Alli typically produces milder gastrointestinal effects whilst still supporting weight management. However, the lower dose means reduced fat-blocking effectiveness compared to 120mg formulations.
Making Your Choice: Value vs Brand Preference
Choose generic orlistat 120mg if cost-effectiveness is your priority - you'll receive identical clinical benefits at lower cost. Opt for branded Xenical if you prefer the original Roche formulation or have previous positive experience with the brand. Both require the same online clinical assessment by our UK-licensed prescribers and follow identical prescribing guidelines for adults with appropriate BMI levels.
Order Today with Free Clinical Assessment
Both orlistat and Xenical are available following online clinical assessment by qualified UK healthcare professionals. Complete our confidential health questionnaire, receive prescriber review, and benefit from next-day delivery across the UK. Use code EDM10 for 10% off your order, whether choosing cost-effective generic orlistat or branded Xenical. All medications dispensed by our MHRA-regulated pharmacy in Leicester.


