Orlistat vs Xenical: Which Should You Choose?
Clinical Equivalence: Same Medicine, Different Price
Orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through the body, which may support weight management when used alongside a reduced-calorie, lower-fat diet. Clinically, there is no difference in how these medicines work - the choice comes down to personal preference and budget.
Cost Comparison: Significant Savings with Generic Orlistat
Generic Orlistat offers substantial cost savings compared to branded Xenical. A 4-week supply costs £32.99 (£29.69 with EDM10) for Orlistat versus £42.99 (£38.69 with EDM10) for Xenical - saving over £100 annually. For longer courses, the savings are even greater: 12-week Orlistat supply costs £95.99 (£86.39 with code), whilst Xenical costs £128.99 (£116.09 with code). Both require prescription following clinical assessment by UK-licensed prescribers.
Safety Profile: Both Medicines Share Identical Side Effects
Orlistat and Xenical have identical safety profiles since they contain the same active ingredient. Common gastrointestinal side effects include oily stools, increased bowel frequency, and urgent need to open bowels. These effects are more likely with high-fat meals but can be minimised by keeping dietary fat intake to approximately 15g per meal. Both medicines may reduce absorption of fat-soluble vitamins, so a daily multivitamin taken at bedtime is recommended.
Alli 60mg: Lower-Strength Alternative
Alli 60mg contains half the dose of prescription-strength orlistat. This lower-strength option may be suitable for those preferring a gentler starting point, though it blocks a smaller proportion of dietary fat. Alli costs £28.99 for a 4-week supply (£26.09 with EDM10). Like prescription-strength options, Alli works best alongside a reduced-calorie, lower-fat diet and regular physical activity.
Online Prescription Process at EverydayMeds
Both Orlistat and Xenical are available following online clinical assessment. Complete our medical questionnaire covering health history, current medications, and BMI information. UK-licensed prescribers review applications and issue prescriptions where clinically appropriate. Treatment suitability is assessed individually - not everyone will be eligible. Our GPhC-registered Leicester pharmacy dispenses and dispatches with next-day tracked delivery across the UK.
Making Your Decision: Value vs Brand Preference
Choose generic Orlistat if cost-effectiveness is your priority - identical clinical effects at significantly lower cost. Some patients prefer branded Xenical for consistency with previous treatment or personal preference. Both options require the same commitment to dietary changes and lifestyle modification for successful weight management. Use code EDM10 at checkout for 10% off every order, making treatment even more affordable.
