Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing Orlistat and Xenical for weight loss results, the most important fact is that both contain exactly the same active ingredient at identical 120mg doses. Generic Orlistat and branded Xenical work through the same mechanism — blocking approximately one third of dietary fat absorption in your digestive system. The clinical effect is identical, making this purely a choice between cost and brand preference.
At EverydayMeds, generic Orlistat 120mg costs £29.69 for a 4-week supply (with EDM10 discount), whilst branded Xenical costs £38.69 for the same period. This represents savings of £9 monthly with generic Orlistat, or £108 annually — significant savings for identical clinical results.
Alli 60mg: The Lower-Strength Alternative
Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. Whilst clinically less potent than 120mg options, Alli may be suitable for those preferring a lower-strength starting point. At £26.09 for a 4-week supply (with EDM10), Alli offers another option for weight management support alongside dietary changes.
How All Three Products Work
Whether you choose Orlistat 120mg, Xenical 120mg, or Alli 60mg, the mechanism remains the same. These medications work by inhibiting lipase enzymes in your gut, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body, helping reduce calorie intake from dietary fat when used alongside a reduced-calorie, lower-fat diet.
Clinical Assessment and Prescription Process
Orlistat 120mg and Xenical 120mg require prescription following clinical assessment. Our UK-licensed prescribers review your medical history, current medications, and BMI information through a comprehensive online consultation. Treatment may be suitable for adults with a BMI of 30kg/m² or above, or 28kg/m² with weight-related health factors such as type 2 diabetes or high blood pressure.
Making Your Decision
Choose generic Orlistat if cost-effectiveness is your priority — you'll receive identical clinical benefits at the lowest price. Opt for branded Xenical if you prefer the original Roche formulation and don't mind paying extra for the brand name. Consider Alli 60mg if you want to start with a lower dose and assess your response to orlistat treatment.
All options are dispensed by our GPhC-registered pharmacy with next-day delivery across the UK. Complete your online assessment today and get 10% off your first order with code EDM10.
