Orlistat vs Xenical: Does Xenical Work on Existing Fat?

pricing for mounjaro and wegovy weight loss

Both Orlistat 120mg and Xenical 120mg contain the same active ingredient and work identically on dietary fat absorption. The key difference is price – generic Orlistat starts from £29.69 for 4 weeks with EDM10, whilst branded Xenical costs £38.69 for the same supply. Both block approximately one third of dietary fat when used alongside a reduced-calorie, lower-fat diet. Choose based on your budget preference – both require prescription following online clinical assessment by our UK-licensed prescribers. Get 10% off every order with code EDM10.

  • Same active ingredient – identical clinical effect on fat absorption
  • Generic Orlistat saves £9 per month compared to branded Xenical
  • Both available with next day delivery from our Leicester-based pharmacy
  • 10% discount on all orders with code EDM10 – new and returning customers
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Should You Choose: Generic or Branded Orlistat?

Same Active Ingredient, Different Price Points

Generic Orlistat 120mg and branded Xenical 120mg contain identical active ingredients at the same dose. Both work by blocking approximately one third of dietary fat absorption in your gut. The clinical effect is identical – the main difference is cost. Our generic Orlistat 4-week supply costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10), representing potential savings of over £100 annually when choosing generic.

How Both Products Work on Dietary Fat

Neither Orlistat nor Xenical work on existing body fat stores. Instead, both inhibit lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. Both products work best when combined with a reduced-calorie, lower-fat diet containing no more than 15g fat per meal to minimise gastrointestinal side effects.

Available Pack Sizes and Pricing

Both generic Orlistat and branded Xenical are available in multiple pack sizes. For Orlistat 120mg: 2-week supply (42 capsules) £15.20 with EDM10, 8-week supply (168 capsules) £57.59 with EDM10, and 12-week supply (252 capsules) £86.39 with EDM10. Xenical pricing: 2-week supply £19.35 with EDM10, 8-week supply £78.29 with EDM10, and 12-week supply £116.09 with EDM10. Larger packs offer better value per capsule.

Alternative: Alli 60mg Lower-Strength Option

For those preferring a lower-strength starting point, Alli 60mg contains half the dose of prescription-strength orlistat. Available as 4-week supply (42 capsules) £26.09 with EDM10, 8-week supply (84 capsules) £49.49 with EDM10, and 12-week supply (252 capsules) £116.99 with EDM10. Alli typically causes milder side effects but blocks less dietary fat absorption.

Online Prescription Process

Both Orlistat and Xenical require prescription following clinical assessment. Complete our online health questionnaire, which includes medical history, current medications, and BMI information. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Your chosen medication is then dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly with next day tracked delivery across the UK.

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