Orlistat vs Xenical: Which Option Should You Choose?
Same Clinical Effect, Different Price Points
Both Orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose. They work by blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in the gut. The key difference lies in cost - generic Orlistat offers substantial savings without compromising clinical effectiveness.
Orlistat 120mg Pricing (Generic)
Our generic Orlistat provides excellent value: 2-week supply (42 capsules) £15.20 with EDM10, 4-week supply (84 capsules) £29.69 with EDM10, 8-week supply (168 capsules) £57.59 with EDM10, and 12-week supply (252 capsules) £86.39 with EDM10. This represents the most cost-effective option for long-term weight management support.
Xenical 120mg Pricing (Branded)
Xenical, manufactured by Roche, costs: 2-week supply £19.35 with EDM10, 4-week supply £38.69 with EDM10, 8-week supply £78.29 with EDM10, and 12-week supply £116.09 with EDM10. Some patients prefer the branded option, though clinical outcomes remain identical to generic Orlistat.
Can Orlistat Cause Constipation?
Constipation is not commonly reported with either Orlistat or Xenical. The most frequent side effects are oily stools, increased bowel movement frequency, and urgent need to open bowels - essentially the opposite of constipation. These gastrointestinal effects result from unabsorbed fat passing through the digestive system and can be minimised by keeping meals low in fat (approximately 15g per meal).
Alli 60mg Alternative
For those preferring lower-strength treatment, Alli 60mg offers half the dose of prescription orlistat. Available without prescription, Alli typically causes milder side effects but blocks less dietary fat. Pricing starts from £26.09 for a 4-week supply with code EDM10.
Online Prescription Process
Both Orlistat and Xenical require prescription following clinical assessment by our UK-licensed prescribers. Complete our online health questionnaire covering medical history, current medications, and BMI information. If treatment is deemed appropriate, your medication will be dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next-day tracked delivery across the UK.
Making Your Decision
Choose generic Orlistat 120mg for maximum value without compromising effectiveness - saving over £100 annually compared to Xenical. Select Xenical 120mg if you prefer branded medication from Roche. Both work identically when used alongside a reduced-calorie, lower-fat diet and regular physical activity.


