Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in your gut, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your digestive system. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical.
Price Comparison: Significant Savings Available
The main difference lies in cost. Generic orlistat offers substantial savings versus Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you save approximately £27 choosing generic orlistat at £86.39 versus Xenical at £116.09 with our EDM10 discount.
Why Some Choose Xenical Over Generic
Despite identical clinical effects, some patients prefer branded Xenical manufactured by Roche. Brand preference is personal choice - both products undergo the same MHRA regulatory standards. Whether you choose orlistat or Xenical, you receive prescription-strength fat blocking medication dispensed by our GPhC-registered pharmacy in Leicester.
Consider Alli 60mg as Lower-Strength Alternative
Alli 60mg provides half the dose of prescription orlistat, blocking a smaller proportion of dietary fat. At £26.09 for 4 weeks with EDM10, Alli may suit those preferring a gentler starting approach. However, prescription-strength orlistat 120mg or Xenical typically provide more significant support for weight management alongside your reduced-calorie, lower-fat diet.
Both Require Clinical Assessment
Orlistat and Xenical are prescription-only medicines requiring clinical assessment by UK-licensed prescribers. Our online consultation reviews your BMI, medical history, and weight-related health factors. Treatment may be suitable for adults with BMI of 30 or above, or 28 and above with conditions like type 2 diabetes or high blood pressure.
Managing Side Effects with Both Products
Gastrointestinal side effects like oily stools and urgent bowel movements affect both orlistat and Xenical equally, as they contain identical active ingredients. Keep meals low in fat (approximately 15g per meal) to minimise side effects significantly. Most patients find side effects reduce as they adapt to lower-fat eating patterns.
Fast Access Through EverydayMeds
Skip GP waiting times with our regulated online prescription service. Complete your clinical assessment, receive prescriber review, and get next day delivery across the UK. Both orlistat and Xenical are dispatched discreetly from our Leicester pharmacy. Use code EDM10 for 10% off every order - available for new and returning customers.


