Which Should You Choose: Orlistat or Xenical?
Blood Pressure and Orlistat: The Facts
Orlistat does not raise blood pressure. Neither generic orlistat 120mg nor branded Xenical 120mg affect blood pressure levels—they work locally in the gut to block approximately one third of dietary fat absorption without entering the bloodstream significantly. In fact, orlistat may be prescribed for patients with high blood pressure who have a BMI of 28 kg/m² or above, as weight management can support blood pressure control alongside medical treatment.
Orlistat vs Xenical: Clinical Equivalence
Generic orlistat 120mg and branded Xenical 120mg are clinically identical. Both contain the same active ingredient at the same dose, work through the same mechanism, and produce equivalent clinical effects. The key difference is cost—choosing generic orlistat saves approximately £9 per month compared to Xenical. At EverydayMeds, orlistat 4-week supply costs £29.69 with EDM10, while Xenical costs £38.69.
Cost Comparison: Your Savings
Generic orlistat offers substantial savings: 2-week supply from £15.20 (vs Xenical £19.35), 4-week supply £29.69 (vs £38.69), 8-week supply £57.59 (vs £78.29), and 12-week supply £86.39 (vs £116.09). All prices include 10% discount with code EDM10. Over 12 weeks, choosing orlistat saves nearly £30 compared to branded Xenical—with identical clinical benefits.
Alli 60mg: Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat. Available without prescription, Alli may suit those preferring a gentler starting point. However, clinical studies demonstrate greater weight management support with 120mg prescription strength. Alli 4-week supply costs £26.09 with EDM10. Following clinical assessment, your prescriber can advise whether 120mg prescription strength would be more suitable.
How Both Products Work
Orlistat and Xenical work identically—inhibiting lipase enzymes in the digestive system to prevent absorption of approximately one third of dietary fat. Unabsorbed fat passes naturally through the body. Both require three capsules daily with main meals containing fat, alongside a reduced-calorie, lower-fat diet and increased physical activity. Maximum daily fat intake should not exceed 30% of calories to minimise gastrointestinal side effects.
Online Prescription Process
Both orlistat and Xenical require prescription following clinical assessment by a UK-licensed prescriber. Complete our online health questionnaire covering medical history, current medications, and weight management goals. Our prescriber reviews your information and issues a prescription where clinically appropriate. All medication is dispensed by our GPhC-registered Leicester pharmacy with next day delivery across the UK.
Making Your Choice
Choose generic orlistat for identical clinical benefits at lower cost, or select branded Xenical if you prefer the original formulation. Both options include prescription consultation, dispensing by qualified pharmacists, and discreet next day delivery. Remember code EDM10 for 10% off every order. Start your clinical assessment today to access prescription-strength weight management support.


