Which orlistat option should you choose?
Orlistat vs Xenical: The Key Differences
Generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by blocking approximately one third of dietary fat absorption when taken alongside a reduced-calorie, lower-fat diet. The primary difference lies in cost and manufacturer—generic orlistat offers significant savings without compromising clinical effectiveness.
At EverydayMeds, generic orlistat 84 capsules (4-week supply) costs £32.99, reduced to £29.69 with discount code EDM10. The same quantity of branded Xenical costs £42.99 (£38.69 with EDM10). Over a typical 12-week treatment course, choosing generic orlistat can save you over £25 compared to Xenical.
Clinical Effectiveness: No Difference Between Products
Both generic orlistat and Xenical deliver identical weight management support when used correctly. Each 120mg capsule works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, potentially supporting weight reduction as part of a structured programme including diet and exercise.
Some patients prefer branded Xenical for peace of mind, while others choose generic orlistat for better value. Both require prescription following clinical assessment and are dispensed by the same GPhC-registered pharmacy standards.
Alli 60mg: The Lower-Strength Alternative
Alli contains orlistat at half the prescription dose (60mg versus 120mg). While less potent than prescription-strength options, Alli may suit those preferring a gentler starting point. An 84-capsule pack (8-week supply) costs £54.99 (£49.49 with EDM10). Three capsules daily are taken with main meals containing fat, following the same timing guidance as prescription-strength orlistat.
Making Your Decision: Value vs Brand Preference
Your choice between orlistat and Xenical depends on personal preference and budget considerations. If clinical effectiveness matters most, generic orlistat delivers identical results at lower cost. If you prefer branded medication, Xenical provides the same orlistat formulation from established manufacturer Roche.
Both options require the same online clinical assessment process. Our UK-licensed prescribers review your medical history, current medications, and weight management goals before determining suitability. Treatment is prescribed only where clinically appropriate following individual assessment.
Complete Your Assessment Today
Ready to start your weight management journey? Complete our online clinical questionnaire for professional review. All three orlistat options—generic 120mg, Xenical 120mg, and Alli 60mg—are available subject to prescriber approval. Orders placed before 3pm receive next-day delivery across the UK.
Remember to use discount code EDM10 for 10% off your order. Whether you choose cost-effective generic orlistat or prefer branded Xenical, you'll receive the same professional service from our Leicester-based GPhC-registered pharmacy.


