Generic vs Branded: Making Your Choice
Orlistat vs Xenical: The Key Differences
When deciding between Orlistat and Xenical, the most important fact is that both contain exactly the same active ingredient at the same 120mg dose. Orlistat is the generic version, whilst Xenical is the branded version manufactured by Roche. Clinically, they work identically - both block approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Price Comparison: Significant Savings with Generic
The main difference lies in cost. Generic Orlistat 84 capsules (4-week supply) costs £32.99, or £29.69 with code EDM10. The same quantity of branded Xenical costs £42.99, or £38.69 with EDM10 - that's approximately £9 more per month. For a 12-week supply, Orlistat costs £86.39 with EDM10, compared to Xenical at £116.09 with EDM10, saving you nearly £30.
Which Should You Choose?
Your choice between Orlistat and Xenical is primarily personal preference and budget. Some patients prefer the reassurance of a branded product, whilst others choose generic Orlistat for the cost savings without compromising on clinical effect. Both are prescription-only medicines requiring clinical assessment by our UK-licensed prescribers.
Alli 60mg: The Lower-Strength Alternative
Also available is Alli 60mg - half the dose of prescription-strength orlistat. At £26.09 for 4 weeks (with EDM10), Alli may be suitable for those preferring a lower-strength starting point, though it blocks a smaller proportion of dietary fat compared to the 120mg prescription options.
How All Three Products Work
Whether you choose Orlistat, Xenical, or Alli, the mechanism is identical. Each works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. This process supports weight management when combined with a reduced-calorie, lower-fat diet and regular physical activity.
Getting Your Prescription
All 120mg orlistat products require prescription following clinical assessment. Complete our online health questionnaire, reviewed by qualified UK-licensed prescribers. If clinically appropriate, your chosen treatment is dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available.
Start Your Assessment Today
Ready to begin? Choose generic Orlistat for maximum savings, branded Xenical for the original formulation, or Alli 60mg for lower-strength support. Use code EDM10 for 10% off every order. Complete your online clinical assessment now and get your prescription-strength weight loss support delivered tomorrow.


