Orlistat vs Xenical: What's the Difference?

pricing for mounjaro and wegovy weight loss

Orlistat and Xenical both contain the same active ingredient at the same strength (120mg), but there's one key difference: price. Generic orlistat costs from £15.20 for 2 weeks with code EDM10, whilst branded Xenical costs from £19.35. Both work identically to block approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Following an online clinical assessment by our UK-licensed prescribers, you can access either option through our GPhC-registered pharmacy with next day delivery. Choose the most cost-effective option or your preferred brand - the clinical effect is identical.

  • Same active ingredient and dose - clinically identical effects
  • Generic orlistat saves approximately £9 per month vs Xenical
  • Both require prescription following online clinical assessment
  • 10% off every order with code EDM10 - new and returning customers
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Which Should You Choose: Orlistat or Xenical?

Orlistat vs Xenical: The Key Facts

The primary difference between orlistat and Xenical is cost, not clinical effectiveness. Both contain exactly the same active ingredient (orlistat) at the same strength (120mg per capsule). Generic orlistat offers significant savings - a 4-week supply costs £29.69 with EDM10, compared to £38.69 for branded Xenical. That's a saving of approximately £9 per month, or over £100 annually.

How Both Products Work

Whether you choose orlistat or Xenical, the mechanism is identical. Both work by inhibiting lipase enzymes in your digestive system, blocking approximately one third of the fat you eat from being absorbed. The unabsorbed fat passes naturally through your body. This can support weight management when used alongside a reduced-calorie, lower-fat diet and regular physical activity.

Pricing Comparison

Our current pricing with 10% discount (code EDM10) shows clear savings with generic orlistat: 2-week supply - Orlistat £15.20 vs Xenical £19.35. 4-week supply - Orlistat £29.69 vs Xenical £38.69. 8-week supply - Orlistat £57.59 vs Xenical £78.29. 12-week supply - Orlistat £86.39 vs Xenical £116.09. The savings increase with longer treatment courses.

What About Alli 60mg?

Alli contains half the dose of orlistat (60mg vs 120mg) and is clinically less potent. It may be suitable for those preferring a lower-strength starting point. A 4-week supply costs £26.09 with EDM10. However, prescription-strength orlistat or Xenical at 120mg offers greater support for weight management.

Making Your Decision

Choose generic orlistat if cost-effectiveness is your priority - you'll receive the same clinical benefit at a lower price. Choose Xenical if you prefer the branded option from Roche. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy. Following your consultation, treatment can be delivered discreetly to your address with next day delivery available across the UK.

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