Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: The Key Differences
Orlistat 120mg and Xenical 120mg are clinically equivalent treatments containing the same active ingredient at identical doses. The primary difference lies in cost and branding. Generic orlistat offers substantial savings - a 4-week supply costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Both work by blocking approximately one third of dietary fat absorption in the gut, supporting weight management when used alongside a reduced-calorie, lower-fat diet.
What To Eat On Orlistat or Xenical
Your diet is crucial for treatment success and minimising side effects. Keep fat intake to approximately 15g per meal - roughly 30% of total daily calories from fat. High-fat meals significantly increase gastrointestinal side effects including oily stools, urgent bowel movements, and oily discharge. Spread fat intake evenly across three main meals. Choose lean proteins, vegetables, fruits, and whole grains. Take your capsule immediately before, during, or up to one hour after each main meal containing fat.
Consider Alli 60mg as an Alternative
Alli 60mg provides half the dose of prescription-strength orlistat and may suit those preferring a lower-strength starting point. At £28.99 for a 4-week supply (£26.09 with EDM10), Alli typically produces milder side effects whilst still supporting weight management. However, the lower dose means it blocks a smaller proportion of dietary fat compared to the 120mg prescription options.
Cost Comparison: Making Your Decision
Over 12 weeks, generic orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10) - a saving of £29.70. Both require the same clinical assessment and prescription process. Some patients prefer the reassurance of the original branded Xenical, whilst others choose generic orlistat for better value. The clinical effect remains identical regardless of your choice.
Getting Your Prescription
Complete our online clinical assessment for review by a UK-licensed prescriber. Treatment is prescribed where clinically appropriate for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Your prescription is included in the price - no separate GP appointment needed. All medication is dispensed by our GPhC-registered Leicester pharmacy with discreet next day delivery across the UK.


