Which Orlistat Option Should You Choose?
Orlistat vs Xenical: Clinical Effectiveness
Both generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Clinically, they work in the same way - inhibiting lipase enzymes in your gut to prevent absorption of approximately one third of dietary fat from each meal. The unabsorbed fat passes naturally through your digestive system. Success rates are equivalent between generic and branded versions, as the mechanism of action and dosing remain identical.
Price Comparison: Significant Savings Available
The primary difference lies in cost. Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10) - representing savings of approximately £9 monthly. Over a 12-week course, choosing generic orlistat saves £33+ compared to Xenical. Both require the same online clinical assessment and are dispensed by our GPhC-registered pharmacy with identical next day delivery service.
Alli 60mg: Lower-Strength Alternative
Alli 60mg offers half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. At £28.99 for 4 weeks (£26.09 with EDM10), it provides an option for those preferring a lower-strength starting point, though clinical effects are correspondingly reduced compared to 120mg formulations.
Online Prescription Process
Both orlistat and Xenical require prescription following clinical assessment. Complete our online health questionnaire covering medical history, current medications and BMI information. A UK-licensed prescriber reviews your details and issues a prescription where clinically appropriate. Treatment is suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions, when used alongside a reduced-calorie, lower-fat diet.
Expected Results and Success Factors
Success with either option depends primarily on dietary compliance rather than brand choice. Both may help reduce calorie intake from dietary fat as part of a structured weight management programme. Keeping meals to approximately 15g fat each significantly improves tolerability and effectiveness. Most patients experience gastrointestinal side effects initially, which typically reduce as diet adapts to lower fat intake.
Making Your Decision
Choose generic orlistat 120mg for maximum value without compromising clinical effect. Select Xenical if you prefer the branded option from Roche. Consider Alli 60mg for a gentler introduction, though effectiveness is correspondingly lower. All three options are available through our regulated online service with 10% discount using EDM10.
