Which Should You Choose: Generic Orlistat or Xenical?
Orlistat vs Xenical: Identical Effect, Different Cost
The key decision between generic Orlistat 120mg and branded Xenical 120mg is cost rather than clinical effect. Both contain exactly the same active ingredient at identical 120mg strength, meaning they work in precisely the same way by inhibiting lipase enzymes to block approximately one third of dietary fat absorption.
Generic Orlistat 4-week supply costs £32.99 (£29.69 with EDM10), whilst Xenical 4-week supply costs £42.99 (£38.69 with EDM10) - representing a saving of approximately £9 monthly with the generic option. Over a 12-week treatment course, you could save £29.70 by choosing generic Orlistat (£86.39 with EDM10) versus Xenical (£116.09 with EDM10).
Can Orlistat Affect Your Periods?
Both Orlistat and Xenical may cause menstrual irregularities in some women, listed as an uncommon side effect affecting up to 1 in 100 people. This appears to be related to weight loss and changes in body fat distribution rather than direct hormonal effects, as orlistat acts locally in the gut and is not significantly absorbed into the bloodstream.
If you experience changes to your menstrual cycle whilst taking either Orlistat or Xenical, discuss this with your prescriber. Such changes may also indicate pregnancy, during which orlistat should not be used. Both medications require the same clinical assessment and monitoring regardless of which version you choose.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat, costing £49.49 for 8 weeks with EDM10. Whilst clinically less potent than 120mg versions, Alli may be suitable for those preferring a gentler starting approach. However, for maximum clinical benefit, most prescribers recommend the full 120mg strength when clinically appropriate.
Making Your Purchase Decision
Choose generic Orlistat 120mg if cost-effectiveness is your priority - you'll receive identical clinical benefits at the lowest price. Select Xenical 120mg if you prefer the branded option from Roche. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy in Leicester.
Your 12-week supply options: Orlistat £86.39 with EDM10 versus Xenical £116.09 with EDM10. Both include prescription, clinical assessment, and next day delivery. Complete your online consultation today to determine which option suits your needs and budget best.
