Orlistat vs Xenical: Which Should You Choose?
The Key Difference: Price, Not Performance
Generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients at identical doses. Both block approximately one third of dietary fat absorption through the same mechanism — inhibiting lipase enzymes in your gut. The clinical effect is equivalent, making your choice primarily about cost preference rather than effectiveness.
Cost Comparison: Significant Savings Available
Generic orlistat offers substantial savings over branded Xenical. A 4-week supply (84 capsules) costs £29.69 with EDM10 versus £38.69 for Xenical — saving £9 monthly or £108 annually. For 12-week supplies, generic orlistat costs £86.39 compared to Xenical's £116.09, representing £29.70 quarterly savings. Both require the same prescription process and clinical assessment.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. At £26.09 for 4 weeks with EDM10, it offers a gentler starting point for those preferring lower-dose treatment. However, clinical effectiveness is correspondingly reduced compared to 120mg formulations.
Prescription Process: Identical for Both Options
Whether choosing generic orlistat or branded Xenical, the prescription process remains identical. Complete our online health questionnaire covering medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment and issues a prescription where clinically appropriate. Both are dispensed by our GPhC-registered Leicester pharmacy with next day delivery.
Clinical Suitability: Same Criteria Apply
Suitability criteria are identical for orlistat and Xenical. Both may be prescribed for adults with BMI 30+ or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure. Neither is available over the counter at 120mg strength — prescription-only status applies to both generic and branded formulations following individual clinical assessment.
Making Your Decision: Value vs Brand Preference
Choose generic orlistat for maximum value without compromising clinical effectiveness. The £38+ annual savings make it ideal for cost-conscious patients. Select branded Xenical if you prefer Roche's established formulation. Both deliver identical fat-blocking effects when used alongside reduced-calorie, lower-fat diets. Start your assessment today with 10% off using code EDM10.


