Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: The Clinical Facts
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by inhibiting lipase enzymes in the gut to block absorption of approximately one third of dietary fat. This unabsorbed fat passes naturally through the body, potentially supporting weight management when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Price Comparison: Significant Savings Available
The main difference between these prescription medicines is cost. At EverydayMeds, generic orlistat 84 capsules (4-week supply) costs £32.99, reduced to £29.69 with discount code EDM10. Branded Xenical costs £42.99 for the same quantity, or £38.69 with EDM10 - that's £9 more per month for the same clinical effect.
For longer treatment periods, the savings increase substantially. A 12-week supply of generic orlistat costs £86.39 with EDM10 versus £116.09 for Xenical - saving £29.70 over three months whilst receiving identical therapeutic benefits.
Consider Alli 60mg as an Alternative
Alli 60mg provides half the strength of prescription orlistat, designed for those preferring a lower-dose starting point. At £26.09 for a 4-week supply with EDM10, Alli offers another option for weight management support alongside dietary changes.
Making Your Decision
Choose generic orlistat 120mg if you want maximum value whilst receiving the full clinical benefits of this prescription weight loss medication. The generic version undergoes the same rigorous quality standards and provides identical therapeutic effects to Xenical.
Some patients prefer branded Xenical, manufactured by Roche, for brand recognition. Both options require the same online clinical assessment by UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy in Leicester.
What to Expect in Your First Month
Whether you choose orlistat or Xenical, individual responses vary significantly. Both medications work best when dietary fat intake is kept low (approximately 15g per meal) to minimise gastrointestinal side effects. Most patients find side effects reduce over time as their diet adapts to lower fat intake.
Getting Your Prescription
Complete our online health questionnaire covering your medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment and issues a prescription where clinically appropriate. Your medication is then dispensed by our registered pharmacy and delivered discreetly to your address with next day delivery available.
Both orlistat and Xenical are prescription-only medicines requiring individual clinical assessment. Treatment suitability depends on factors including BMI, medical history, and weight-related health conditions such as type 2 diabetes or high blood pressure.


