Orlistat vs Xenical: Which Should You Buy?

pricing for mounjaro and wegovy weight loss

Orlistat 120mg and Xenical 120mg contain identical active ingredients and deliver the same clinical effect. The key difference is price: generic orlistat from £15.20 versus branded Xenical from £19.35 (with EDM10). Both are prescription-only medicines that work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Following an online clinical assessment by our UK-licensed prescribers, you can choose the option that suits your budget. Save 10% on every order with code EDM10. Start your clinical assessment today.

  • Same active ingredient - orlistat 120mg in both products
  • Significant savings with generic orlistat - £9+ per month cheaper
  • Both require prescription following online clinical assessment
  • 10% off every order with code EDM10 - new and returning customers
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Generic or Branded: Making Your Choice

Orlistat vs Xenical: The Essential Facts

Orlistat 120mg and Xenical 120mg are clinically equivalent medicines containing the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your body, supporting weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.

The primary difference between these medications is cost. Generic orlistat offers substantial savings: a 4-week supply costs £29.69 with EDM10 compared to £38.69 for branded Xenical - saving you over £100 annually. Both medicines deliver the same clinical effect and are subject to the same UK regulatory standards.

Pricing Comparison: Orlistat vs Xenical

Generic orlistat 120mg pricing (with EDM10): 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39. Xenical 120mg pricing (with EDM10): 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09. The savings with generic orlistat are significant across all pack sizes whilst maintaining identical clinical effectiveness.

Alli 60mg: The Lower-Strength Alternative

Alli 60mg contains half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. This lower-strength option may appeal to those preferring a gentler starting point, though it is clinically less potent than the 120mg prescription versions. Alli pricing with EDM10: 4 weeks £26.09, 8 weeks £49.49, 12 weeks £116.99.

Clinical Assessment Required

Both orlistat and Xenical require a prescription following clinical assessment. Our online consultation process involves completing a medical questionnaire reviewed by UK-licensed prescribers. Treatment is prescribed where clinically appropriate for adults with a BMI of 30 or above, or 28 or above with weight-related health conditions. The assessment ensures the medication is suitable and safe for your individual circumstances.

How Both Medicines Work

Orlistat acts locally in the digestive system, inhibiting pancreatic and gastric lipases that break down dietary fats. Approximately one third of consumed fat cannot be digested and is eliminated naturally. This mechanism works best when combined with meals containing no more than 15g fat each. Both versions may cause gastrointestinal side effects, particularly with high-fat meals, but these typically reduce as your diet adapts.

Ordering Your Preferred Option

Start your clinical assessment today to determine which option suits your needs and budget. Our GPhC-registered pharmacy dispenses both generic orlistat and branded Xenical following prescriber approval. Next day delivery is available across the UK with discreet, tracked packaging. Use code EDM10 for 10% off your order, whether you choose cost-effective orlistat or prefer branded Xenical.

How it
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Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

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