Which Should You Choose: Orlistat or Xenical?
The Key Difference: Price, Not Performance
When comparing orlistat and Xenical, the most important factor is cost. Both contain exactly 120mg of the same active ingredient - orlistat - at identical doses. Generic orlistat offers substantial savings: £86.39 for a 12-week supply with EDM10 compared to £116.09 for branded Xenical. That's nearly £30 saved for the same clinical effect.
How Both Products Work Identically
Whether you choose generic orlistat or branded Xenical, the mechanism is identical. Both work by blocking lipase enzymes in your gut, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. This fat-blocking action supports weight management when used alongside a reduced-calorie, lower-fat diet and regular physical activity.
Orlistat 120mg - Best Value Option
Generic orlistat 120mg provides clinically equivalent results at the lowest cost. Available in multiple pack sizes: 2 weeks (£15.20 with EDM10), 4 weeks (£29.69), 8 weeks (£57.59), or 12 weeks (£86.39). Each capsule contains 120mg orlistat, taken three times daily with main meals containing fat. Following online clinical assessment by a UK-licensed prescriber, orlistat can be prescribed where clinically appropriate for adults with suitable BMI and health profile.
Xenical 120mg - The Original Brand
Xenical 120mg by Roche delivers the same orlistat effect but costs more: 2 weeks (£19.35 with EDM10), 4 weeks (£38.69), 8 weeks (£78.29), or 12 weeks (£116.09). Some patients prefer branded medication, though the clinical outcome remains identical to generic orlistat. The same online prescription process applies, with assessment by qualified UK prescribers and supply through our GPhC-registered Leicester pharmacy.
Consider Alli 60mg as Alternative
Alli 60mg offers half the dose of prescription-strength orlistat. While less potent than 120mg formulations, Alli may suit those preferring lower-strength treatment. Available at £26.09 for 4 weeks, £49.49 for 8 weeks, or £116.99 for 12 weeks with EDM10. No prescription required for this lower-dose version.
Making Your Decision
Choose generic orlistat for maximum savings without compromising effectiveness. Choose Xenical if you prefer branded medication and don't mind the higher cost. Both require commitment to a lower-fat diet to minimise gastrointestinal side effects and maximise weight management support. Complete your online clinical assessment today to determine suitability and start your chosen treatment.


