Orlistat vs Xenical: Which Should You Choose?
Identical Active Ingredient, Different Price
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at the same dose. They work identically by blocking approximately one third of dietary fat absorption in your gut. The clinical effect is equivalent - the key difference is cost. Generic orlistat offers significant savings: 4-week supply costs £29.69 with EDM10 versus Xenical at £38.69. Over 12 weeks, you save nearly £30 choosing generic orlistat.
Can You Take Orlistat with Other Weight Loss Medications?
Our UK-licensed prescribers assess medication interactions as part of your clinical review. If you're considering orlistat alongside other treatments like Mounjaro (semaglutide), this requires careful evaluation. Each person's medical history, current medications, and health circumstances are assessed individually. Your prescriber will determine whether orlistat is appropriate and safe alongside any existing treatments.
Complete Range Available
We stock three orlistat options: Generic orlistat 120mg (most cost-effective), branded Xenical 120mg (same effect, higher price), and Alli 60mg (lower strength alternative). Orlistat 120mg requires prescription following clinical assessment. All strengths work by the same mechanism - blocking lipase enzymes to reduce dietary fat absorption by approximately one third.
Pricing Comparison
Generic orlistat 120mg: 2 weeks £15.20, 4 weeks £29.69, 8 weeks £57.59, 12 weeks £86.39 (with EDM10). Xenical 120mg: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 (with EDM10). Alli 60mg: 4 weeks £26.09, 8 weeks £49.49, 12 weeks £116.99 (with EDM10).
Order Process
Complete our online health questionnaire including current medications and medical history. A UK-licensed prescriber reviews your information and assesses suitability. If appropriate, your prescription is issued and dispensed by our GPhC-registered pharmacy in Leicester. Next day delivery available across the UK with discreet, tracked packaging.


