Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When choosing between orlistat and Xenical for weight management, understanding the differences helps you make the right decision. Both contain orlistat 120mg as the active ingredient and work identically by blocking approximately one third of dietary fat absorption. Generic orlistat costs £29.69 for a 4-week supply with EDM10, while branded Xenical costs £38.69 – a monthly saving of £9 when choosing generic. Some patients prefer branded Xenical, whilst others choose generic orlistat for better value without compromising clinical effect.
Why Choose Generic Orlistat 120mg?
Generic orlistat offers the most cost-effective weight management option without sacrificing clinical effectiveness. At £29.69 for 84 capsules (4-week supply) with code EDM10, you save significantly compared to Xenical whilst receiving identical treatment. Our generic orlistat is sourced through licensed UK pharmaceutical supply chains and dispensed by our GPhC-registered pharmacy in Leicester. All 4 pack sizes available: 2-week (£15.20), 4-week (£29.69), 8-week (£57.59), and 12-week (£86.39) supplies with EDM10 discount.
When to Consider Xenical 120mg
Some patients prefer branded Xenical manufactured by Roche, particularly those who have previously used the branded version successfully. Xenical costs £38.69 for 84 capsules (4-week supply) with EDM10 – £9 more than generic but still competitively priced for branded treatment. Available in the same 4 pack sizes: 2-week (£19.35), 4-week (£38.69), 8-week (£78.29), and 12-week (£116.09) supplies. Both orlistat and Xenical require prescription following clinical assessment by our UK-licensed prescribers.
Alli 60mg: Lower-Strength Alternative
Alli provides orlistat at half the prescription strength (60mg versus 120mg) for those preferring a gentler starting point. At £26.09 for a 4-week supply with EDM10, Alli may be suitable for adults seeking lower-strength fat blocking support. Available as 4-week (£26.09), 8-week (£49.49), and 12-week (£116.99) supplies. All three options work by inhibiting lipase enzymes in the gut, preventing absorption of approximately one third of dietary fat when used alongside a reduced-calorie, lower-fat diet.
How All Three Options Work
Whether you choose orlistat, Xenical, or Alli, the mechanism remains consistent. Each works locally in the digestive system by blocking lipase enzymes responsible for breaking down dietary fat. Approximately one third of consumed fat passes through the body unabsorbed, supporting weight management when combined with appropriate dietary changes. The unabsorbed fat is eliminated naturally, which may cause gastrointestinal side effects that reduce when keeping meals low in fat content.
Order Online with Clinical Assessment
All three products require clinical assessment by our UK-licensed prescribers through our online consultation process. Complete your medical questionnaire, receive prescriber review, and if suitable, your chosen treatment will be dispensed by our GPhC-registered Leicester pharmacy. Next day delivery available across the UK with discreet packaging. Use code EDM10 for 10% off every order. Start your clinical assessment today to access prescription-strength weight management support.


