Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
When considering weight management medication, many patients wonder whether Orlistat or Xenical works on carbohydrates. The answer is neither - both medications work exclusively on dietary fat absorption, blocking approximately one third of the fat you consume. Orlistat 120mg (generic) and Xenical 120mg (branded) contain identical active ingredients at the same dose, providing clinically equivalent effects. The primary difference lies in cost, with generic Orlistat offering substantial savings without compromising effectiveness.
How Both Medications Work (Not on Carbohydrates)
Orlistat and Xenical work by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This mechanism is specific to fat only - neither medication affects carbohydrate, protein, or alcohol absorption. The unabsorbed fat passes naturally through your body, which may cause gastrointestinal side effects if meals contain high fat content. Both medications must be used alongside a reduced-calorie, lower-fat diet and regular physical activity for optimal results.
Orlistat Pricing: Better Value Option
Generic Orlistat 120mg offers significant cost savings compared to branded Xenical. At EverydayMeds, Orlistat costs £29.69 for a 4-week supply (84 capsules) with code EDM10, whilst Xenical costs £38.69 for the same supply - a saving of £9 per month. For longer treatment periods, the savings increase: 12-week Orlistat supply costs £86.39 versus Xenical at £116.09, representing a £30 saving with identical clinical effectiveness.
Xenical: The Branded Alternative
Xenical 120mg, manufactured by Roche, offers the same orlistat 120mg formulation in a branded package. Some patients prefer Xenical due to brand recognition, whilst others choose generic Orlistat for value. Both require prescription following clinical assessment by our UK-licensed prescribers. Xenical pricing starts from £19.35 for 2 weeks with EDM10 discount code applied at checkout.
Alli 60mg: Lower-Strength Alternative
For those seeking a gentler introduction to orlistat treatment, Alli 60mg provides half the prescription dose. At £26.09 for 4 weeks with EDM10, Alli may suit patients preferring lower-strength treatment or those concerned about gastrointestinal side effects. However, the reduced dose means less dietary fat blocking compared to prescription-strength options.
Order Your Preferred Option Today
Whether you choose cost-effective Orlistat or branded Xenical, both require online clinical assessment by our qualified UK prescribers. Complete your consultation today to determine suitability, then select your preferred medication strength and supply duration. Apply code EDM10 for 10% off every order, with next-day delivery available across the UK from our GPhC-registered Leicester pharmacy.


