Orlistat vs Xenical: Which Should You Buy?
How Both Orlistat and Xenical Work
Generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and work through the same mechanism. Both inhibit lipase enzymes in your digestive system, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body, helping reduce calorie intake when used alongside a reduced-calorie, lower-fat diet. Neither acts on your brain - both work locally in your gut with minimal absorption into your bloodstream.
Price Comparison: Orlistat vs Xenical
The primary difference between orlistat and Xenical is cost. Generic orlistat 84 capsules (4-week supply) costs £32.99, reduced to £29.69 with code EDM10. Equivalent Xenical 84 capsules cost £42.99, reduced to £38.69 with EDM10. Over 12 weeks, you save approximately £30 choosing generic orlistat (£86.39) versus Xenical (£116.09). Both deliver identical clinical benefits - the only difference is your investment.
Clinical Effectiveness: No Difference
Both orlistat and Xenical demonstrate identical clinical effectiveness because they contain the same 120mg orlistat dose. Each blocks approximately one third of dietary fat absorption when taken three times daily with main meals. Side effects, dosing schedules, and contraindications remain identical. Your weight management results depend on dietary compliance and lifestyle changes, not whether you choose generic or branded versions.
Which Option to Choose
Choose generic orlistat 120mg for maximum value without compromising effectiveness. At £29.69 for 4 weeks with EDM10, it offers substantial savings versus Xenical at £38.69. Some patients prefer branded Xenical for reassurance, though clinical outcomes remain identical. Both require prescription following online assessment by UK-licensed prescribers. Consider Alli 60mg at £26.09 for 4 weeks if you prefer starting with lower-strength treatment.
Getting Your Prescription
Both orlistat and Xenical require prescription following clinical assessment. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. UK-licensed prescribers review your information and issue prescriptions where clinically appropriate. All medication is dispensed by our GPhC-registered pharmacy in Leicester with next day delivery across the UK. Your prescription is included in the price - no separate GP appointment needed.
Available Pack Sizes
Both orlistat and Xenical are available in multiple pack sizes to suit your treatment duration. 42-capsule packs provide 2-week supplies, whilst 252-capsule packs cover 12 weeks of treatment. Longer packs offer better value per capsule. Use code EDM10 at checkout for 10% off every order, whether you're a new or returning customer. All orders include free standard delivery with tracked next day delivery available.


