Which Should You Buy: Generic or Branded?
Orlistat vs Xenical: Heart Safety Profile
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients at the same dose. This means their cardiovascular safety profiles are identical. Orlistat works locally in the gut by blocking lipase enzymes, preventing approximately one third of dietary fat from being absorbed. Unlike stimulant weight loss medications that affect the heart directly, orlistat acts only in the digestive system and is not absorbed into the bloodstream in significant amounts.
Price Comparison: Significant Savings Available
The main difference between orlistat and Xenical is cost. Generic orlistat 4-week supply costs £32.99 (£29.69 with EDM10), whilst branded Xenical costs £42.99 (£38.69 with EDM10). Over 12 weeks, you save £33 choosing generic orlistat at £95.99 versus Xenical at £128.99. Both products require the same clinical assessment and deliver identical results.
Clinical Assessment Process
Whether you choose orlistat or Xenical, both require review by a UK-licensed prescriber. Complete our online health questionnaire covering your medical history, current medications, and weight management goals. Our prescriber will assess your suitability for either treatment option. Orlistat may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure.
Alli 60mg: Lower Strength Alternative
For those preferring a gentler starting point, Alli 60mg offers half the dose of prescription-strength orlistat. At £54.99 for 8 weeks (£49.49 with EDM10), Alli blocks a smaller proportion of dietary fat and typically causes milder side effects. However, the clinical effect is proportionally reduced compared to 120mg formulations.
Making Your Decision
Choose generic orlistat 120mg if budget is your priority - you'll get identical clinical results at lower cost. Choose Xenical 120mg if you prefer branded medication from Roche. Both work by the same mechanism, blocking approximately one third of dietary fat when taken with each main meal. Side effects are identical and manageable by keeping meals low in fat (around 15g per meal).
Order Today with 10% Discount
Get your preferred treatment delivered next day from our GPhC-registered Leicester pharmacy. Use code EDM10 for 10% off every order. Prescription assessment is included - no separate GP appointment needed. All medication is sourced through MHRA-regulated supply chains and dispensed by qualified UK pharmacists.


