Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Facts
When comparing Xenical tablets 120mg against generic orlistat 120mg, the most important fact to understand is that both contain exactly the same active ingredient at identical doses. Orlistat 120mg is the generic version, whilst Xenical 120mg is the branded version manufactured by Roche. Clinically, both work in precisely the same way - inhibiting lipase enzymes to block approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Price Comparison: Significant Savings Available
The primary difference lies in cost. Generic orlistat 120mg costs £29.69 for a 4-week supply (84 capsules) with code EDM10, compared to £38.69 for branded Xenical 120mg - a saving of £9 monthly. Over 12 weeks, generic orlistat costs £86.39 versus £116.09 for Xenical, representing a £30 saving. Both options require the same prescription following clinical assessment by our UK-licensed prescribers.
Treatment Options at EverydayMeds
We offer three orlistat-based treatments. Orlistat 120mg provides the most cost-effective option, available in 2-week (£15.20), 4-week (£29.69), 8-week (£57.59), and 12-week (£86.39) supplies with EDM10. Xenical 120mg offers the branded alternative at £19.35 (2 weeks), £38.69 (4 weeks), £78.29 (8 weeks), and £116.09 (12 weeks) with discount. For those preferring lower-strength treatment, Alli 60mg provides half the dose, starting from £26.09 for 4 weeks.
How Both Medications Work
Whether you choose generic orlistat or branded Xenical, the mechanism remains identical. Both work locally in the gut to inhibit lipase enzymes responsible for breaking down dietary fat. This prevents approximately one third of consumed fat from being absorbed, with unabsorbed fat passing naturally through the digestive system. Neither product affects carbohydrates, proteins, or acts on the brain - they work purely in the digestive tract.
Clinical Assessment Process
Both orlistat 120mg and Xenical 120mg require prescription following online clinical assessment. Our UK-licensed prescribers review your medical history, current medications, BMI, and suitability for treatment. The process typically involves completing a health questionnaire, prescriber review, and if clinically appropriate, prescription issuance. Treatment may be suitable for adults with BMI 30 or above, or BMI 28 or above with weight-related health conditions.
Making Your Decision
Choose generic orlistat 120mg if cost is your primary concern - you'll receive identical clinical benefits at the lowest price. Opt for Xenical 120mg if you prefer branded medication from Roche. Consider Alli 60mg if you want to start with lower-strength treatment. All three options are dispensed by our GPhC-registered pharmacy with next day delivery available. Complete your online consultation today and use code EDM10 for 10% off every order.


