Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: What's the Difference?
Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. The key difference is price - generic orlistat offers significant savings whilst providing the same clinical effect. Both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Your choice often comes down to personal preference and budget considerations.
Generic Orlistat 120mg - Best Value Option
Generic orlistat provides excellent value for money. Our 4-week supply costs £32.99 (£29.69 with EDM10), whilst 12-week supplies cost £95.99 (£86.39 with code EDM10). This represents substantial savings compared to branded alternatives. The clinical effect remains identical - you're simply choosing the most cost-effective option for your weight management journey.
Xenical 120mg - The Branded Choice
Some patients prefer branded Xenical, manufactured by Roche. Our Xenical prices start from £21.50 for 2 weeks (£19.35 with EDM10) and £42.99 for 4 weeks (£38.69 with EDM10). Whilst more expensive than generic orlistat, some patients value the branded option. The active ingredient and clinical effect remain identical to generic orlistat.
Alli 60mg - Lower Strength Alternative
Alli contains half the dose of prescription-strength orlistat. At 60mg per capsule, it blocks a smaller proportion of dietary fat compared to 120mg products. Our Alli prices start from £28.99 for 4 weeks (£26.09 with EDM10). This may suit those preferring a lower-strength starting point or experiencing side effects with 120mg doses.
How Both Products Work
Whether you choose orlistat or Xenical, both work identically by inhibiting lipase enzymes in your digestive system. This blocks approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. Both must be used alongside a reduced-calorie, lower-fat diet and taken three times daily with meals containing fat.
Online Prescription Process
Both orlistat and Xenical require prescription-only access through clinical assessment. Complete our online health questionnaire, reviewed by UK-licensed prescribers. If clinically appropriate, your prescription is dispensed by our GPhC-registered pharmacy and delivered discreetly to your address. The prescription is included in the price - no separate GP visit required.
Managing Side Effects
Both products may cause gastrointestinal side effects, particularly when eating high-fat meals. Keep each meal to approximately 15g fat or less to minimise oily stools, urgency, or abdominal discomfort. These effects indicate the medication is working and typically reduce as your diet adapts. Most patients find side effects manageable with proper dietary adjustments.
