Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing orlistat 120mg and Xenical 120mg, the most important fact is they contain identical active ingredients at exactly the same dose. Both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. The primary difference lies in cost and branding.
Generic orlistat 120mg capsules cost £29.69 for a 4-week supply (84 capsules) with code EDM10, whilst branded Xenical costs £38.69 for the same quantity. Over 12 weeks, you could save £30 by choosing generic orlistat over Xenical - both delivering clinically equivalent results.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg contains half the dose of prescription-strength orlistat, making it suitable for those preferring a gentler starting point. At £26.09 for a 4-week supply with EDM10, Alli blocks a smaller proportion of dietary fat compared to the 120mg prescription options. All three products require the same dietary approach - keeping meals low in fat to maximise effectiveness and minimise side effects.
How All Three Products Work
Whether you choose orlistat 120mg, Xenical 120mg, or Alli 60mg, the mechanism remains the same. Each works locally in your digestive system by inhibiting lipase enzymes responsible for breaking down dietary fat. This means approximately one third of the fat you eat passes through your body unabsorbed, reducing calorie intake from dietary fat.
The unabsorbed fat is naturally excreted, which can cause gastrointestinal side effects - particularly when eating high-fat meals. Keeping your fat intake to roughly 15g per meal significantly reduces these side effects whilst maintaining the medication's effectiveness.
Pricing Comparison: Best Value Options
For the most cost-effective weight management support, generic orlistat 120mg offers excellent value. A 12-week supply costs £86.39 with EDM10 compared to £116.09 for Xenical - saving you nearly £30. For shorter treatment periods, 8-week supplies cost £57.59 (orlistat) versus £78.29 (Xenical).
If you prefer starting with a lower dose, Alli 60mg at £49.49 for 8 weeks with EDM10 provides an intermediate option. Remember, all prices include the prescription fee and clinical assessment - no separate GP appointment needed.
Making Your Decision
Choose generic orlistat 120mg if you want the most cost-effective option with full prescription strength. Select Xenical 120mg if you prefer the original branded version despite the higher cost. Consider Alli 60mg if you'd like to start with a lower dose before potentially progressing to prescription strength.
Complete your online clinical assessment today. Following review by a UK-licensed prescriber, your chosen treatment will be dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address with next day delivery available.


