Orlistat vs Xenical: Which to Buy With Metformin?

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Wondering whether you can take orlistat and metformin together? Both generic orlistat 120mg and branded Xenical 120mg contain the same active ingredient and may be prescribed alongside metformin for weight management in adults with type 2 diabetes. The key difference is price - generic orlistat costs from £15.20 for 2 weeks versus Xenical at £19.35 (with EDM10 discount). Both require an online clinical assessment by our UK-licensed prescribers. Order today with next day delivery from our GPhC-registered Leicester pharmacy. Use code EDM10 for 10% off every order.

  • Same clinical effect - orlistat and Xenical both contain 120mg orlistat
  • Save £9+ per month choosing generic orlistat over branded Xenical
  • May be prescribed with metformin following clinical assessment
  • Next day delivery from GPhC-registered UK pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Generic Orlistat vs Branded Xenical - Price Comparison

Can You Take Orlistat and Metformin Together?

Many adults with type 2 diabetes wonder whether orlistat can be taken alongside metformin. Both medications may be prescribed together as part of a comprehensive weight management programme, subject to individual clinical assessment by a qualified UK-licensed prescriber. Orlistat works by blocking approximately one third of dietary fat absorption, while metformin helps control blood glucose levels. When used together alongside a reduced-calorie, lower-fat diet, they may support weight management in adults with diabetes-related weight concerns.

Orlistat vs Xenical: What's the Difference?

The choice between generic orlistat 120mg and branded Xenical 120mg comes down to cost rather than clinical effect. Both contain exactly the same active ingredient at the same 120mg dose, meaning they work identically in your body. Generic orlistat costs £29.69 for 4 weeks (with EDM10), while Xenical costs £38.69 - a saving of £9 per month. Both require the same prescription process and clinical assessment. Whether you choose orlistat or Xenical, you'll get the same fat-blocking effect when taken three times daily with meals containing fat.

Which Should You Choose?

Most patients choose generic orlistat 120mg for the significant cost savings - over £36 saved on a 12-week course compared to Xenical. At £86.39 for 12 weeks (with EDM10 discount), generic orlistat offers excellent value while delivering identical clinical results. However, some patients prefer branded Xenical for personal preference. Both options are available following online clinical assessment by our UK-licensed prescribers, dispensed from our GPhC-registered pharmacy in Leicester.

Alli 60mg: The Lower-Strength Alternative

For those preferring a lower-strength option, Alli 60mg contains half the dose of prescription orlistat. While less potent than 120mg versions, Alli may cause fewer gastrointestinal side effects and is available from £26.09 for 4 weeks (with EDM10). Like prescription-strength orlistat, it works by blocking dietary fat absorption and must be used alongside a reduced-calorie, lower-fat diet for best results.

Order Online Today

Ready to start your weight management journey? Complete our online clinical assessment to see if orlistat or Xenical is suitable for you. Our UK-licensed prescribers will review your information and issue a prescription where clinically appropriate. Choose from 2-week to 12-week supplies with next day delivery across the UK. Remember to use code EDM10 for 10% off your order - applicable to both new and returning customers.

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