Which Should You Choose: Generic Orlistat or Branded Xenical?
Orlistat vs Xenical: The Key Differences
When choosing between Orlistat 120mg and Xenical 120mg, the fundamental difference is cost rather than clinical effect. Both medications contain identical amounts of the same active ingredient - orlistat 120mg - and work by blocking approximately one third of dietary fat absorption. Generic Orlistat from £15.20 (with EDM10) offers substantial savings compared to branded Xenical from £19.35 (with EDM10), while delivering the same mechanism of action.
Price Comparison: Orlistat vs Xenical
Our pricing demonstrates significant savings with generic Orlistat. A 4-week supply (84 capsules) costs £29.69 with EDM10 versus £38.69 for Xenical - saving you £9 monthly. Over a 12-week treatment period, you'll save £29.70 choosing Orlistat (£86.39) over Xenical (£116.09). Both medications require the same dosing - one capsule three times daily with main meals containing fat.
Clinical Equivalence and Effectiveness
Orlistat 120mg and Xenical 120mg are clinically equivalent, containing identical active ingredients at the same therapeutic dose. Both work as lipase inhibitors in the digestive system, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through the body. Whether you choose generic Orlistat or branded Xenical, the mechanism of action, side effect profile, and potential effectiveness remain identical when used alongside a reduced-calorie, lower-fat diet.
Alli 60mg: The Lower-Strength Alternative
For those preferring a lower-strength starting point, Alli 60mg offers half the dose of prescription orlistat. Priced from £26.09 (with EDM10) for a 4-week supply, Alli may result in milder gastrointestinal side effects whilst still supporting weight management. However, the lower dose means it blocks a smaller proportion of dietary fat compared to the 120mg prescription strength options.
Online Prescription Process
Both Orlistat and Xenical require prescription following clinical assessment. Our online consultation process involves completing a comprehensive health questionnaire reviewed by UK-licensed prescribers. If treatment is deemed appropriate, your prescription is dispensed by our GPhC-registered Leicester pharmacy. The prescription cost is included - no separate GP appointment needed. Treatment is delivered discreetly with next day delivery available across the UK.
Managing Side Effects
Both Orlistat and Xenical may cause gastrointestinal side effects including oily stools, increased bowel movements, and abdominal discomfort. These effects are directly related to dietary fat intake - keeping meals low in fat (approximately 15g per meal) significantly reduces side effects. Most patients find side effects diminish as they adapt to a lower-fat diet. A daily multivitamin taken at bedtime is recommended to replace fat-soluble vitamins.
Buy Orlistat or Xenical Today
Ready to start treatment? Use code EDM10 for 10% off every order, whether choosing cost-effective generic Orlistat or branded Xenical. Both options provide the same clinical benefits when used correctly alongside dietary changes. Complete our online consultation to begin your clinical assessment with our qualified UK prescribers today.


