Which Should You Choose: Orlistat or Xenical?
Generic Orlistat 120mg vs Branded Xenical 120mg
The most important fact when choosing between orlistat and Xenical is that they contain the identical active ingredient at exactly the same strength — 120mg orlistat per capsule. Clinically, there is no difference in how they work or their effectiveness. Both block approximately one third of dietary fat absorption when taken correctly alongside a reduced-calorie, lower-fat diet.
The primary difference is cost. Generic orlistat offers substantial savings: a 4-week supply costs £29.69 with code EDM10, compared to £38.69 for branded Xenical. Over 12 weeks, you'll save £29.70 by choosing generic orlistat (£86.39 vs £116.09 with EDM10).
Best Way to Take Orlistat (Generic or Xenical)
Whether you choose generic orlistat or Xenical, the dosing is identical: one 120mg capsule taken three times daily with each main meal containing fat. Take each capsule immediately before, during, or up to one hour after eating. If you skip a meal or eat a fat-free meal, you can skip that dose.
For optimal results and to minimise gastrointestinal side effects, keep your fat intake to approximately 15g per meal. This lower-fat approach helps the medication work effectively while reducing the likelihood of oily stools or urgent bowel movements that can occur with high-fat meals.
Alli 60mg: The Lower-Strength Alternative
For those preferring a gentler introduction to orlistat treatment, Alli 60mg provides half the dose of prescription-strength versions. While less potent than 120mg formulations, Alli blocks a smaller proportion of dietary fat and typically causes milder side effects. A 4-week supply costs £26.09 with code EDM10.
Online Prescription Process
Both orlistat 120mg and Xenical 120mg require a prescription following clinical assessment. Our streamlined online process involves completing a medical questionnaire reviewed by UK-licensed prescribers. If treatment is deemed appropriate for your circumstances, we'll dispense and dispatch your chosen medication from our GPhC-registered pharmacy in Leicester.
The prescription cost is included in our prices — no separate GP appointment needed. Most patients receive their medication within 24 hours via tracked, discreet delivery.
Making Your Decision
Choose generic orlistat 120mg if you want the most cost-effective option with identical clinical results to Xenical. The £9 monthly saving makes it the practical choice for most patients requiring long-term weight management support.
Choose Xenical 120mg if you prefer the branded version manufactured by Roche. Some patients feel more confident with the original branded medication, though the therapeutic effect remains identical to generic alternatives.
Both options require the same commitment to dietary changes and regular physical activity to achieve meaningful weight management results.
