Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
Generic orlistat 120mg and branded Xenical 120mg are clinically equivalent—both contain exactly the same active ingredient at identical doses. The key difference lies in cost, not effectiveness. A 4-week supply of generic orlistat costs £29.69 with EDM10, whilst Xenical costs £38.69 for the same period. Over 12 weeks, you'll save approximately £30 by choosing generic orlistat (£86.39) over Xenical (£116.09).
Best Foods to Eat on Both Medications
Whether you choose orlistat or Xenical, your diet determines both effectiveness and side effect management. Keep each meal to approximately 15g of fat to minimise gastrointestinal side effects. Best food choices include grilled chicken breast without skin, white fish like cod or haddock, steamed vegetables, brown rice, and fresh fruit. Avoid high-fat meals like fried foods, creamy sauces, or fatty cuts of meat, as these significantly increase the likelihood of oily stools and urgent bowel movements.
Why Choose Generic Orlistat?
Generic orlistat 120mg offers identical clinical benefits at substantial savings. Manufactured to the same rigorous standards and containing the same active ingredient, it blocks approximately one third of dietary fat absorption just like Xenical. Our 8-week supply costs £57.59 with EDM10—that's £20+ less than the equivalent Xenical pack. All our generic orlistat is sourced through licensed UK pharmaceutical supply chains and dispensed by our GPhC-registered pharmacy.
Why Some Choose Xenical
Xenical 120mg, manufactured by Roche, is the original branded version some patients prefer. Whilst clinically identical to generic orlistat, some individuals feel more confident with the branded option. If budget isn't your primary concern and you prefer the established brand, Xenical remains an excellent choice at £38.69 for 4 weeks with EDM10.
Consider Alli 60mg as a Starting Option
For those preferring to start with a lower dose, Alli 60mg offers half the strength of prescription orlistat. At £26.09 for 4 weeks with EDM10, it provides a gentler introduction with typically milder side effects. However, it blocks a smaller proportion of dietary fat compared to the 120mg prescription options.
Order Process and Delivery
Following completion of our online clinical assessment, a UK-licensed prescriber will review your information and issue a prescription where clinically appropriate. Both orlistat and Xenical are prescription-only medicines requiring individual medical review. Once prescribed, we'll dispatch your medication with next-day delivery across the UK. Remember to use code EDM10 at checkout for 10% off your order.


