Choose Your Orlistat: Generic or Branded Xenical?
Orlistat vs Xenical: The Key Facts
Orlistat 120mg and Xenical 120mg are clinically equivalent weight loss medications containing the same active ingredient at identical doses. The fundamental difference lies in cost, not clinical effectiveness. Generic orlistat offers the same fat-blocking mechanism as branded Xenical, inhibiting approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Pricing Comparison: Significant Savings Available
Generic orlistat provides substantial savings compared to branded Xenical. A 4-week supply costs £32.99 (£29.69 with EDM10) versus Xenical at £42.99 (£38.69 with EDM10) - saving you approximately £9 monthly. For longer treatments, choose our 12-week supply: orlistat costs £95.99 (£86.39 with EDM10) while Xenical costs £128.99 (£116.09 with EDM10). Apply discount code EDM10 for 10% off every order.
Same Mechanism, Same Results
Both orlistat and Xenical work by blocking lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body. Neither acts on your brain or affects appetite directly - they work locally in your gut to reduce fat absorption from meals containing fat.
Which Should You Choose?
Choose generic orlistat if you want maximum value without compromising clinical effectiveness. Select Xenical if you prefer the branded Roche formulation. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy in Leicester. Consider Alli 60mg as a lower-strength alternative if you prefer starting with half the prescription dose.
How to Order Both Options
Complete our online clinical questionnaire for prescriber review. Following assessment, your chosen medication is dispensed and dispatched with next day delivery across the UK. Prescription costs are included - no separate GP appointment required. Both orlistat and Xenical are prescription-only medicines requiring individual clinical assessment for suitability.
Important Treatment Information
Both medications must be used alongside a reduced-calorie, lower-fat diet and regular physical activity. Take one capsule three times daily with main meals containing fat. Keep meals to approximately 15g fat each to minimise gastrointestinal side effects. A daily multivitamin taken at bedtime is recommended due to reduced absorption of fat-soluble vitamins.


