Which Should You Buy: Generic or Branded?
Orlistat vs Xenical: The Key Facts
Both orlistat 120mg and Xenical 120mg contain the identical active ingredient at exactly the same dose. They work in precisely the same way - inhibiting lipase enzymes in your gut to block approximately one third of dietary fat absorption. The clinical effect is identical. The main difference lies in cost and manufacturer preference.
Price Comparison: Significant Savings Available
Generic orlistat offers substantial savings versus branded Xenical. A 4-week supply (84 capsules) costs £29.69 for orlistat versus £38.69 for Xenical with code EDM10 - saving you £9 per month. Over a 12-week course, orlistat costs £86.39 compared to Xenical at £116.09, saving £29.70. Both options include prescription and next day delivery from our Leicester-based GPhC-registered pharmacy.
Not the Same as Ozempic
Neither orlistat nor Xenical is the same as Ozempic (semaglutide). Ozempic is an injectable GLP-1 medication that works on appetite centres in the brain. Orlistat and Xenical work locally in your digestive system, blocking dietary fat absorption without affecting your brain or appetite directly. They're completely different medications with different mechanisms of action.
Alli 60mg: The Lower-Strength Alternative
Alli contains orlistat at half the prescription dose (60mg versus 120mg). It blocks a smaller proportion of dietary fat and typically causes milder side effects. Alli 60mg costs £26.09 for a 4-week supply with EDM10. Some patients prefer starting with the lower dose before considering prescription-strength options.
Which Option Should You Choose?
Choose generic orlistat 120mg if you want maximum value while receiving identical clinical benefits. The active ingredient, dose, and effect are the same as Xenical but at a lower cost. Choose Xenical 120mg if you prefer branded medication or have used Xenical successfully before. Both require prescription following clinical assessment by our UK-licensed prescribers.
How to Order Today
Complete our online clinical assessment for either orlistat or Xenical. A qualified UK prescriber will review your information and issue a prescription if clinically appropriate. We'll dispatch your medication from our GPhC-registered pharmacy with next day delivery. Use code EDM10 for 10% off your order. Both options work alongside a reduced-calorie, lower-fat diet for effective weight management.


