Orlistat vs Xenical: Which Should You Choose?
Safe Orlistat Dosing: 120mg vs 60mg Options
The safe, clinically-proven dose for prescription orlistat is 120mg taken three times daily with meals containing fat. Both generic orlistat 120mg and branded Xenical 120mg contain this identical dose, blocking approximately one third of dietary fat absorption. Alli 60mg offers a lower-strength alternative at half the prescription dose. Maximum safe intake is three capsules daily - one with each main meal. If a meal contains no fat or is skipped, the corresponding dose can be omitted.
Orlistat vs Xenical: Clinical Equivalence
Generic orlistat 120mg and Xenical 120mg are clinically equivalent - containing the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to reduce dietary fat absorption by approximately one third. The unabsorbed fat passes naturally through the digestive system. Xenical is manufactured by Roche as the original branded version, while generic orlistat is produced by various licensed manufacturers to the same pharmaceutical standards.
Price Comparison: Significant Savings Available
Generic orlistat offers substantial cost savings versus Xenical without compromising clinical effect. A 4-week supply (84 capsules) costs £32.99 for orlistat versus £42.99 for Xenical - saving £10 monthly. With our EDM10 discount code, prices reduce to £29.69 and £38.69 respectively. Over a 12-week treatment course, generic orlistat costs £86.39 compared to Xenical at £116.09 with EDM10 - a saving of nearly £30.
Alli 60mg: Lower-Strength Alternative
Alli contains 60mg orlistat - half the prescription strength. While less potent than 120mg formulations, it blocks a smaller proportion of dietary fat with typically milder gastrointestinal effects. A 4-week supply costs £26.09 with EDM10. Some patients prefer starting with the lower dose before progressing to prescription strength following clinical assessment.
Safety Profile: What to Expect
Both orlistat 120mg and Xenical 120mg have identical safety profiles. The most common side effects are gastrointestinal - including oily stools, increased bowel movement frequency, and abdominal discomfort. These effects are directly related to dietary fat intake and significantly reduce when meals contain less than 15g fat. Side effects indicate the medication is working by blocking fat absorption. Taking a multivitamin supplement at bedtime helps maintain fat-soluble vitamin levels.
Which Option is Right for You?
Choose generic orlistat 120mg for maximum value without compromising effectiveness. Select Xenical 120mg if you prefer the original branded formulation. Consider Alli 60mg for a gentler starting approach. All options require clinical assessment by our UK-licensed prescribers to ensure suitability. Treatment works best alongside a reduced-calorie, lower-fat diet and regular physical activity. Complete your online consultation today to begin your weight management journey.


