Compare Orlistat vs Xenical: Make Your Choice Today
Orlistat vs Xenical: Identical Effect, Different Price
The most important fact when choosing between orlistat and Xenical is that both contain exactly the same active ingredient at the same 120mg dose. Clinically, they are equivalent - both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. The primary difference lies in cost and manufacturer preference.
Generic orlistat 120mg costs £32.99 for a 4-week supply (£29.69 with EDM10), whilst branded Xenical costs £42.99 for the same period (£38.69 with EDM10). This represents a saving of approximately £10 monthly when choosing generic orlistat, making it the more cost-effective option for long-term weight management.
Why Choose Private Prescription Over NHS?
NHS orlistat prescriptions are subject to strict eligibility criteria and waiting times for GP appointments. Our private prescription service offers several advantages: immediate online consultation without GP appointment, faster access following clinical assessment, and convenient home delivery. The process involves completing an online health questionnaire reviewed by UK-licensed prescribers, with treatment dispensed by our GPhC-registered pharmacy in Leicester.
Private prescription costs include the clinical assessment, prescription, medication and delivery - no separate GP fees or prescription charges. This streamlined approach is particularly beneficial for busy professionals or those in areas with limited GP availability.
Complete Pricing Comparison: All Pack Sizes
Generic Orlistat 120mg: 2 weeks £16.89 (£15.20 EDM10), 4 weeks £32.99 (£29.69 EDM10), 8 weeks £63.99 (£57.59 EDM10), 12 weeks £95.99 (£86.39 EDM10). Branded Xenical 120mg: 2 weeks £21.50 (£19.35 EDM10), 4 weeks £42.99 (£38.69 EDM10), 8 weeks £86.99 (£78.29 EDM10), 12 weeks £128.99 (£116.09 EDM10).
The savings become more significant with longer treatment courses. A 12-week generic orlistat supply costs £86.39 with discount code EDM10, compared to £116.09 for Xenical - a saving of nearly £30 over three months.
How Both Medications Work
Both orlistat and Xenical work identically by inhibiting lipase enzymes in the gut. This prevents approximately one third of dietary fat from being digested and absorbed. The unabsorbed fat passes naturally through the body, reducing calorie intake from dietary sources. Neither medication acts as an appetite suppressant or stimulant - they work locally in the digestive system.
Success with either medication depends on following a reduced-calorie, lower-fat diet with no more than 30% of daily calories from fat. High-fat meals increase the likelihood of gastrointestinal side effects, whilst lower-fat meals minimise these effects and maximise treatment benefits.
Clinical Assessment Process
Both orlistat and Xenical require prescription following clinical assessment. Our online consultation covers medical history, current medications, BMI calculation and weight-related health factors. UK-licensed prescribers review each application individually, ensuring treatment suitability and safety. This regulatory process maintains the same clinical standards as traditional GP prescribing whilst offering greater convenience and speed.


