Price Comparison: Orlistat vs Xenical vs Alli
Orlistat 120mg vs Xenical 120mg: What's the Difference?
The key difference between orlistat 120mg and Xenical 120mg is cost – not clinical effectiveness. Both contain exactly the same active ingredient (orlistat) at the same 120mg dose. Xenical is the original branded version manufactured by Roche, while orlistat 120mg is the clinically equivalent generic alternative. Both work identically by blocking approximately one third of dietary fat from being absorbed in your digestive system.
Compare Orlistat and Xenical Prices
Our pricing shows significant savings when choosing generic orlistat over branded Xenical. A 4-week supply of orlistat costs £29.69 (with EDM10), compared to £38.69 for Xenical – saving you £9 per month. Over a 12-week course, you'll save £29.70 by choosing orlistat (£86.39) instead of Xenical (£116.09). Both options require the same clinical assessment and prescription from our UK-licensed prescribers.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg offers half the dose of prescription-strength orlistat, making it suitable for those preferring a lower-strength starting point. At £26.09 for a 4-week supply (with EDM10), Alli blocks a smaller proportion of dietary fat compared to the 120mg prescription versions. While less potent than orlistat 120mg or Xenical 120mg, Alli may produce fewer gastrointestinal side effects due to its lower dose.
Which Should You Choose?
Choose generic orlistat 120mg if you want the most cost-effective option with identical clinical benefits to Xenical. Choose Xenical 120mg if you prefer the original branded version and don't mind paying extra. Choose Alli 60mg if you want to start with a lower dose. All three options work by reducing dietary fat absorption when used alongside a reduced-calorie, lower-fat diet and regular physical activity.
How to Order Online
Complete our online clinical assessment to determine your suitability for orlistat, Xenical, or Alli. Our UK-licensed prescribers will review your information and issue a prescription if clinically appropriate. Orders are dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available. Use code EDM10 for 10% off every order.
Clinical Assessment Required
All orlistat products require a clinical assessment before prescription. Our online consultation covers your medical history, current medications, and weight management goals. This replaces the need for a separate GP appointment while maintaining the same clinical standards. Treatment suitability depends on individual health circumstances including BMI and weight-related health factors.


