Orlistat vs Xenical: Which Should You Choose?
What Are Orlistat Capsules Used For?
Orlistat capsules are prescription-only weight loss medication used for weight management in adults with a BMI of 30 kg/m² or above, or 28 kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. The medication works by blocking approximately one third of dietary fat absorption in your digestive system, helping reduce calorie intake when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Orlistat vs Xenical: The Key Differences
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Xenical is the branded version manufactured by Roche, while orlistat is the generic equivalent. Clinically, they work identically - blocking the same amount of dietary fat absorption with the same side effect profile. The primary difference is cost, with generic orlistat offering significant savings without compromising effectiveness.
Price Comparison: Orlistat vs Xenical at EverydayMeds
Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), while branded Xenical costs £42.99 (£38.69 with EDM10). For 12-week supplies, orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10). This represents monthly savings of approximately £9-10 when choosing generic orlistat over Xenical, with identical clinical outcomes. Use code EDM10 for 10% off every order.
How Both Medications Work
Whether you choose orlistat or Xenical, the mechanism is identical. The medication inhibits lipase enzymes in your gut, preventing approximately one third of dietary fat from being digested and absorbed. This unabsorbed fat passes naturally through your body. The medication acts locally in your digestive system and is not significantly absorbed into your bloodstream. Both work best when each meal contains no more than 15g fat to minimise gastrointestinal side effects.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat and is available for those preferring a lower-strength starting point. At EverydayMeds, Alli costs £28.99 for 4 weeks (£26.09 with EDM10). While less potent than prescription 120mg options, Alli may suit individuals wanting milder effects with potentially fewer side effects.
Getting Your Prescription Online
Both orlistat and Xenical require prescription following clinical assessment by UK-licensed prescribers. Our online consultation replaces traditional GP appointments - complete a medical questionnaire covering your health history, current medications, and BMI details. Following prescriber review and approval, your medication is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next day delivery available across the UK.
Which Should You Choose?
If you want identical clinical effects at the lowest cost, choose generic orlistat 120mg. If you prefer branded medication and don't mind paying extra, Xenical remains an excellent choice. Both require the same reduced-calorie, lower-fat diet approach and produce the same weight management support. Your prescriber can discuss which option suits your preferences and budget during your online consultation.
