Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Facts
Generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in your gut, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. Clinically, they are equivalent - the main difference is cost.
Price Comparison: Significant Savings with Generic
The price difference between orlistat and Xenical is substantial. Generic orlistat 4-week supply costs £29.69 with EDM10, while Xenical costs £38.69 - that's £9 more monthly for the identical clinical effect. Over 12 weeks, you save £29.70 choosing generic orlistat (£86.39) versus Xenical (£116.09). Both options are available following online clinical assessment by our UK-licensed prescribers.
Which Patients Choose Which Option?
Most patients choose generic orlistat for the cost savings, knowing they're getting the same clinical benefit. Some prefer branded Xenical, often due to familiarity with the name. Both are manufactured to identical UK pharmaceutical standards and delivered from our GPhC-registered pharmacy in Leicester. Your prescriber can help you decide which option suits your needs and budget best.
Consider Alli 60mg as Lower-Strength Alternative
For those preferring to start with lower-strength orlistat, Alli 60mg offers half the dose of prescription-strength versions. At £26.09 for 4 weeks with EDM10, Alli provides a gentler introduction to orlistat treatment, typically with milder gastrointestinal side effects. However, the clinical effect is proportionally reduced compared to 120mg versions.
How to Order: Same Process for Both
Whether choosing generic orlistat or Xenical, the ordering process is identical. Complete our online health questionnaire, including BMI and medical history details. Our UK-licensed prescriber reviews your information and, where clinically appropriate, issues your prescription. We dispatch from our Leicester pharmacy with next day delivery across the UK. Use code EDM10 for 10% off every order.
Taking Orlistat: Three Times Daily with Meals
Both orlistat and Xenical are taken three capsules daily - one with each main meal containing fat. Take immediately before, during, or up to one hour after eating. If you miss a meal or eat a fat-free meal, skip that dose. This dosing schedule applies whether you choose generic orlistat or branded Xenical, as both contain identical 120mg orlistat.
Side Effects: Identical for Both Products
Side effects are identical between generic orlistat and Xenical, as they contain the same active ingredient. Common gastrointestinal effects include oily stools, increased bowel frequency, and oily spotting. These effects are more likely with high-fat meals and can be minimised by keeping fat intake to approximately 15g per meal. Always use alongside a reduced-calorie, lower-fat diet for best results.


