Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing orlistat 120mg with Xenical 120mg, you're looking at clinically equivalent medications. Both contain the same active ingredient at identical doses and work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The primary difference lies in cost and branding – Xenical is the original branded version manufactured by Roche, whilst orlistat 120mg is the generic alternative.
Price Comparison: Significant Savings Available
Generic orlistat offers substantial cost savings compared to branded Xenical. A 4-week supply (84 capsules) of orlistat costs £29.69 with code EDM10, whilst Xenical costs £38.69 – that's a saving of £9 per month. Over a 12-week treatment course, you could save over £30 by choosing generic orlistat at £86.39 versus Xenical at £116.09.
Clinical Effectiveness: Identical Results
Both orlistat and Xenical deliver the same clinical outcomes when used alongside a reduced-calorie, lower-fat diet. They work locally in the digestive system, preventing approximately one third of consumed dietary fat from being absorbed. The unabsorbed fat passes naturally through the body. Whether you choose generic or branded, the mechanism of action and potential for supporting weight management remains identical.
Consider Alli 60mg as an Alternative
For those seeking a lower-strength option, Alli 60mg provides half the dose of prescription-strength orlistat. At £26.09 for a 4-week supply with EDM10, Alli offers a gentler introduction to orlistat treatment, though with correspondingly reduced fat-blocking potential. This option doesn't require a prescription and may cause milder gastrointestinal side effects.
Side Effects: Same Profile for Both
Both orlistat and Xenical share identical side effect profiles, as they contain the same active ingredient. Common gastrointestinal effects include oily stools, increased bowel movement frequency, and flatulence with discharge. These effects can be minimised by keeping meals low in fat – approximately 15g fat per meal is recommended.
Which Option Should You Choose?
Your choice between orlistat and Xenical may depend on personal preference and budget. Generic orlistat provides excellent value whilst delivering identical clinical benefits. Some patients prefer branded Xenical for the assurance of the original formulation. Both require prescription following clinical assessment by a UK-licensed prescriber through our online consultation process.
Order Today with 10% Discount
Whether you choose cost-effective generic orlistat or branded Xenical, both are available through our secure online service. Complete your clinical assessment today, and if prescribed, benefit from next day delivery across the UK. Use code EDM10 for 10% off every order, making effective weight management support more accessible than ever.


