Which Should You Choose: Generic Orlistat or Branded Xenical?
Orlistat vs Xenical: Identical Clinical Effects
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at the same dose. They work identically by blocking approximately one third of dietary fat absorption in your gut. The key difference is cost - generic orlistat offers the same clinical effect as branded Xenical but at a significantly lower price. Some patients prefer branded Xenical, whilst others choose generic orlistat for better value.
Cost Comparison: Orlistat vs Xenical Pricing
Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), whilst Xenical 120mg costs £42.99 for the same 4-week supply (£38.69 with EDM10). Over 12 weeks, you save approximately £27 choosing generic orlistat. For 8-week supplies, orlistat costs £57.59 with EDM10 compared to Xenical at £78.29 - a saving of over £20. Both options include prescription following clinical assessment by our UK-licensed prescribers.
How to Take Orlistat or Xenical for Weight Loss
Take one 120mg capsule with each main meal containing fat, up to three times daily. Take immediately before, during, or up to one hour after eating. If you miss a meal or eat a meal with no fat, you can skip that dose. Both orlistat and Xenical must be used alongside a reduced-calorie, lower-fat diet with no more than 30% of calories from fat. Keep fat intake to approximately 15g per meal to minimise gastrointestinal side effects.
Alternative Option: Alli 60mg
Alli 60mg contains half the dose of prescription-strength orlistat. Whilst clinically less potent than 120mg versions, it may be suitable for those preferring a lower-strength starting point. Alli costs £26.09 for 4 weeks with EDM10. Take one 60mg capsule with each main meal containing fat, following the same timing guidelines as prescription-strength versions.
Online Prescription Process
Complete our online health questionnaire covering medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment and issues a prescription where clinically appropriate. Treatment is suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Your medication is dispensed by our GPhC-registered pharmacy and delivered discreetly next day across the UK.
Managing Side Effects
Both orlistat and Xenical may cause gastrointestinal side effects including oily stools, increased bowel movements, and urgent need to open bowels. These effects are more common with high-fat meals and typically reduce as you adapt to a lower-fat diet. Keep dietary fat low and consider wearing dark underwear or panty liner during initial treatment. Side effects indicate the medication is working by preventing fat absorption.
