Generic Orlistat vs Branded Xenical: Making Your Choice
Orlistat vs Xenical: What's the Same?
Both orlistat 120mg capsules and Xenical 120mg capsules contain exactly the same active ingredient (orlistat) at identical strength. They work by blocking approximately one third of dietary fat absorption in your gut, supporting weight management alongside a reduced-calorie, lower-fat diet. The clinical effect, dosing (one capsule three times daily with meals), and side effect profile are identical between generic orlistat and branded Xenical.
The Key Difference: Price
Generic orlistat offers significant savings compared to branded Xenical. A 4-week supply of orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10) — saving you approximately £9 per month with the generic option. Over a 12-week course, you could save nearly £30 by choosing orlistat over Xenical.
Which Should You Choose?
Your choice between orlistat and Xenical may depend on personal preference and budget. Some patients prefer the assurance of a well-known branded medicine like Xenical, whilst others prioritise the cost savings of generic orlistat. Both options require the same online clinical assessment by our UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy with identical service standards.
Alternative: Alli 60mg
For those considering a lower-strength option, Alli 60mg contains half the dose of prescription-strength orlistat. Priced from £26.09 with EDM10, Alli may suit those preferring to start with a gentler approach, though it blocks a smaller proportion of dietary fat than the 120mg prescription versions.
How to Order Your Chosen Option
Complete our online health questionnaire to begin your clinical assessment. Our UK-licensed prescriber will review your information and determine whether orlistat treatment is suitable for you. If approved, you can choose between generic orlistat (from £15.20 with EDM10) or branded Xenical (from £19.35 with EDM10). Both are dispatched with next day delivery from our Leicester-based GPhC-registered pharmacy.
Pack Sizes and Pricing
Both orlistat and Xenical are available in convenient pack sizes. For orlistat: 42 capsules (2 weeks, £15.20 with EDM10), 84 capsules (4 weeks, £29.69), 168 capsules (8 weeks, £57.59), or 252 capsules (12 weeks, £86.39). Xenical pricing: 42 capsules (£19.35 with EDM10), 84 capsules (£38.69), 168 capsules (£78.29), or 252 capsules (£116.09). Use code EDM10 for 10% off every order.


