Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Clinical Facts
Orlistat 120mg and Xenical 120mg are clinically equivalent medications containing the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through the digestive system, which explains why both products have similar gastrointestinal side effects profiles.
Does Orlistat Make You Constipated?
Constipation is not a common side effect of orlistat or Xenical. The most frequently reported gastrointestinal effects are actually the opposite - loose, oily stools, increased bowel movement frequency, and urgent need to open bowels. These occur because unabsorbed fat passes through the digestive system. Very common side effects (affecting more than 1 in 10 people) include oily or fatty stools, oily spotting, and abdominal discomfort. These effects are more pronounced when eating high-fat meals and typically reduce when following a lower-fat diet.
Price Comparison: Significant Savings with Generic
The primary difference between orlistat and Xenical is cost. Our 4-week supply pricing shows clear savings with generic orlistat at £32.99 (£29.69 with EDM10) versus Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you save approximately £33 choosing orlistat at £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10). Both options require the same online clinical assessment and provide identical weight management support when used alongside a reduced-calorie, lower-fat diet.
Consider Alli 60mg as Alternative
Alli 60mg offers half the dose of prescription-strength orlistat, potentially with milder gastrointestinal side effects. At £28.99 for 4 weeks (£26.09 with EDM10), it provides a lower-strength option for those preferring a gentler starting point. However, the clinical effect is correspondingly reduced compared to 120mg formulations.
Managing Bowel Changes on Orlistat Treatment
Whether choosing orlistat or Xenical, managing dietary fat intake is crucial for minimising gastrointestinal side effects. Keep meals to approximately 15g fat each, spread evenly across three main meals. This approach significantly reduces the likelihood of urgent bowel movements, oily discharge, or abdominal discomfort. Most patients find side effects become more manageable as they adapt their diet during the first few weeks of treatment.
Order Today with Clinical Assessment Included
Both orlistat and Xenical require prescription-only access through clinical assessment by our UK-licensed prescribers. Complete our online health questionnaire covering your medical history, current medications, and BMI information. Following prescriber approval, we'll dispense and dispatch your chosen treatment from our GPhC-registered Leicester pharmacy with next day delivery across the UK.
