Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
The primary difference between orlistat 120mg and Xenical 120mg lies in cost, not clinical effect. Both contain identical amounts of the same active ingredient - orlistat - which works by blocking approximately one third of dietary fat absorption. Generic orlistat 120mg capsules cost £32.99 for 4 weeks (£29.69 with EDM10), whilst branded Xenical costs £42.99 for the same supply (£38.69 with EDM10). This represents savings of over £100 annually when choosing generic orlistat.
Clinical Effect: Identical Results
Whether you choose orlistat or Xenical, the mechanism remains unchanged. Both formulations inhibit lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, supporting weight management when used alongside a reduced-calorie, lower-fat diet. For patients managing epilepsy who require weight management, both options work identically - the choice depends purely on budget preference.
Pricing Comparison: Significant Savings Available
Our Leicester-based GPhC-registered pharmacy offers competitive pricing on both formulations. Orlistat 120mg costs £16.89 for 2 weeks (£15.20 with EDM10), £32.99 for 4 weeks (£29.69 with EDM10), £63.99 for 8 weeks (£57.59 with EDM10), and £95.99 for 12 weeks (£86.39 with EDM10). Xenical costs £21.50 for 2 weeks (£19.35 with EDM10), rising to £128.99 for 12 weeks (£116.09 with EDM10). Code EDM10 provides 10% off every order for both new and returning customers.
Who Chooses Which Option?
Many patients prefer generic orlistat for its cost-effectiveness, particularly for longer treatment periods where savings compound significantly. Others choose branded Xenical, manufactured by Roche, preferring the original formulation. Both require prescription following online clinical assessment by UK-licensed prescribers. For patients taking antiepileptic drugs, prescribers monitor both options equally as orlistat may affect seizure control in some individuals.
Alli 60mg: The Lower-Strength Alternative
Alli 60mg offers half the dose of prescription-strength orlistat, providing a gentler introduction for some patients. At £28.99 for 4 weeks (£26.09 with EDM10), Alli costs more per milligram but may suit those preferring lower-dose treatment. However, the reduced strength means blocking less dietary fat compared to 120mg formulations.
Order Process: Simple Online Assessment
Both orlistat and Xenical require completion of our online health questionnaire, covering medical history, current medications including any epilepsy treatments, and BMI information. UK-licensed prescribers review applications individually, issuing prescriptions where clinically appropriate. Following approval, our Leicester pharmacy dispenses and dispatches your chosen formulation with tracked next-day delivery across the UK.


