Generic vs Branded: Making Your Choice
Orlistat vs Xenical: What's the Difference?
Generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at the same dose. Both work identically by inhibiting lipase enzymes in your digestive system to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your body. Clinically, there is no difference in effectiveness between the generic and branded versions.
Price Comparison: Orlistat vs Xenical UK
The primary difference between orlistat and Xenical is cost. Generic orlistat offers significant savings: 4 weeks costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you save £33 by choosing generic orlistat at £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10). Both options include the prescription following online clinical assessment.
Which Should You Choose?
Your choice between orlistat and Xenical may depend on personal preference and budget. Generic orlistat provides identical clinical results at a lower cost - ideal if you want maximum value. Some patients prefer branded Xenical for the reassurance of the original manufacturer Roche. Both require the same reduced-calorie, lower-fat diet alongside treatment and both may cause similar gastrointestinal side effects when eating high-fat meals.
Alli 60mg: The Lower-Strength Alternative
Alli contains orlistat at half the prescription dose (60mg versus 120mg). Available from £26.09 for 4 weeks with EDM10, Alli blocks a smaller proportion of dietary fat and typically causes milder side effects. However, the lower dose means reduced effectiveness compared to prescription-strength orlistat or Xenical.
How to Order Online
Both orlistat 120mg and Xenical 120mg are prescription-only medicines requiring clinical assessment. Complete our online health questionnaire covering your medical history, current medications and BMI. A UK-licensed prescriber reviews your information and issues a prescription where clinically appropriate. Orders are dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly next day across the UK.
Making the Right Decision
Whether you choose generic orlistat for value or branded Xenical for preference, both support weight management when used alongside a structured diet and exercise programme. Treatment suitability depends on individual clinical assessment - typically for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Use code EDM10 for 10% off every order. Start your clinical assessment today to access either option.


