Orlistat vs Xenical: Which Should You Choose?
Same Medicine, Different Price: Orlistat vs Xenical
Orlistat 120mg and Xenical 120mg are clinically equivalent treatments containing the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The primary difference lies in cost - generic orlistat offers significant savings compared to branded Xenical whilst delivering the same clinical effect.
Gastrointestinal Side Effects: What to Expect
Both orlistat and Xenical may cause similar gastrointestinal side effects, including diarrhoea, oily stools, urgent bowel movements, and flatulence with discharge. These effects occur because unabsorbed fat passes through the digestive system naturally. Side effects are more likely with high-fat meals and typically reduce when dietary fat intake is kept low (approximately 15g per meal). The frequency and severity of side effects are identical between generic orlistat and branded Xenical.
Cost Comparison: Orlistat vs Xenical Pricing
Generic orlistat provides substantial savings over branded Xenical. A 4-week supply of orlistat costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10) - saving approximately £9 per month. For a 12-week supply, orlistat costs £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10) - a saving of over £29. Both options qualify for our 10% discount with code EDM10.
Alli 60mg: Lower Strength Alternative
Alli 60mg offers half the strength of prescription orlistat, providing a gentler introduction for those concerned about side effects. At 60mg, Alli typically produces milder gastrointestinal effects whilst still blocking a portion of dietary fat. Alli costs £28.99 for 4 weeks (£26.09 with EDM10) and requires three capsules daily with main meals containing fat.
Clinical Assessment and Prescription Process
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment by UK-licensed healthcare professionals. Our online consultation process reviews your medical history, current medications, and BMI to determine treatment suitability. Prescriptions are issued where clinically appropriate for adults with BMI 30+ or BMI 28+ with weight-related health conditions. The assessment process is identical regardless of whether you choose generic orlistat or branded Xenical.
Managing Side Effects Effectively
To minimise diarrhoea and other gastrointestinal effects with either orlistat or Xenical, maintain a reduced-calorie, lower-fat diet with no more than 30% of daily calories from fat. Spread fat intake evenly across three main meals, limiting each meal to approximately 15g fat. Consider wearing dark underwear or panty liners during initial treatment. Take a daily multivitamin at bedtime to replace fat-soluble vitamins that may be reduced. If side effects persist or worsen, consult your healthcare professional.
Order Orlistat or Xenical Online Today
Choose generic orlistat for maximum value or branded Xenical if you prefer the original formulation. Both options are available through our GPhC-registered online pharmacy following prescriber approval. Complete your clinical assessment today and receive next day delivery across the UK. Use code EDM10 for 10% off your first and every subsequent order.


