Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
Both Orlistat 120mg and Xenical 120mg contain identical active ingredients and work in exactly the same way - blocking approximately one third of dietary fat absorption. The primary difference lies in cost and branding. Generic Orlistat offers substantial savings, with a 4-week supply costing £29.69 (with EDM10), compared to £38.69 for branded Xenical. Over a 12-week treatment course, choosing generic Orlistat saves approximately £30 compared to Xenical.
Essential Low-Fat Diet Requirements for Both
Whether you choose Orlistat or Xenical, maintaining a low-fat diet is crucial for treatment success and minimising gastrointestinal side effects. Keep daily fat intake to approximately 30% of calories, spreading this evenly across three main meals (roughly 15g fat per meal). High-fat meals significantly increase the likelihood of oily stools, urgent bowel movements, and anal leakage - the most common side effects experienced with both medications.
Comparing Your Options: Complete Price Breakdown
Our transparent pricing helps you make an informed decision. Generic Orlistat 120mg: 2-week supply £15.20, 4-week supply £29.69, 8-week supply £57.59, 12-week supply £86.39 (all with EDM10 discount). Xenical 120mg branded: 2-week supply £19.35, 4-week supply £38.69, 8-week supply £78.29, 12-week supply £116.09 (with EDM10). For those preferring a lower-strength option, Alli 60mg is available from £26.09 for a 4-week supply.
How Both Medications Work With Your Diet
Orlistat and Xenical work identically - they inhibit lipase enzymes in your digestive system to prevent approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, which is why maintaining a low-fat diet is essential. Take one capsule with each main meal containing fat, up to three times daily. If you skip a meal or eat a fat-free meal, you can omit that dose.
Clinical Assessment and Prescription Process
Both Orlistat and Xenical require prescription following clinical assessment. Our UK-licensed prescribers review your online health questionnaire, considering your BMI, medical history, and weight-related health factors. Treatment may be suitable for adults with BMI 30+ or BMI 28+ with conditions like type 2 diabetes or high blood pressure. The assessment process is identical regardless of which option you prefer.
Managing Side Effects: Same Approach for Both
Since both contain identical active ingredients, side effect profiles and management strategies are the same. Most patients experience gastrointestinal effects including oily stools, increased bowel movement frequency, and occasional anal leakage. These effects are directly related to your fat intake - the lower your meal fat content, the fewer side effects you'll experience. Consider a daily multivitamin taken at bedtime, as both medications may reduce absorption of fat-soluble vitamins.
Making Your Final Decision
Choose generic Orlistat if cost-effectiveness is your priority - you'll receive identical clinical benefits at a lower price. Select Xenical if you prefer branded medication and don't mind paying extra for the Roche brand name. Both options are dispensed by our GPhC-registered pharmacy with next-day delivery available. Start your clinical assessment today and our prescribers will confirm which strength and option suits your needs.
