Making Your Choice: Generic vs Branded Orlistat
Orlistat vs Xenical: The Clinical Facts
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by the same mechanism - inhibiting lipase enzymes in your digestive system to block approximately one third of dietary fat absorption. The unabsorbed fat passes naturally through your body. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical.
Price Comparison: Significant Savings Available
The key difference lies in cost. Generic orlistat 120mg costs £16.89 for 2 weeks (£15.20 with EDM10), whilst Xenical costs £21.50 (£19.35 with EDM10). Over 4 weeks, you'll pay £32.99 for orlistat vs £42.99 for Xenical - saving nearly £10 monthly. For longer treatment, a 12-week supply of orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10) - a saving of £33 over three months.
Alli 60mg: The Lower-Strength Alternative
Alli contains half the dose at 60mg orlistat per capsule. This lower strength may suit those preferring a gentler starting point, though it blocks a smaller proportion of dietary fat. Alli costs £28.99 for 4 weeks (£26.09 with EDM10). Like the 120mg versions, it should be taken with each main meal containing fat.
Which Should You Choose?
Choose generic orlistat 120mg if cost is a priority - you'll receive identical clinical benefits at the lowest price. Choose Xenical 120mg if you prefer the original branded version from Roche. Both require the same online clinical assessment by our UK-licensed prescribers. Consider Alli 60mg if you want to start with a lower dose, though prescription-strength 120mg options are more potent for weight management support.
How to Order Your Chosen Treatment
Complete our online health questionnaire for clinical assessment. Our UK-licensed prescribers will review your suitability for orlistat treatment, considering your BMI, medical history and weight-related health factors. If appropriate, your prescription will be dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available.
Important Treatment Information
All orlistat products work best alongside a reduced-calorie, lower-fat diet and regular physical activity. Keep fat intake to approximately 15g per meal to minimise gastrointestinal side effects. Take one capsule with each main meal containing fat, up to three times daily. A daily multivitamin is recommended, taken at bedtime at least 2 hours after your last orlistat dose.


