Orlistat vs Xenical: Which Should You Buy?
How Long Before Orlistat Starts Working
Both orlistat 120mg and Xenical 120mg start working immediately after taking your first capsule. The medication acts locally in your digestive system, blocking lipase enzymes that break down dietary fat. You may notice effects within 24-48 hours of starting treatment, particularly if you eat meals containing fat. Orlistat blocks approximately one third of the fat you eat, with unabsorbed fat passing naturally through your body. The timing is identical whether you choose generic orlistat or branded Xenical - both contain the same 120mg active ingredient.
Orlistat vs Xenical: The Key Differences
Generic orlistat 120mg and branded Xenical 120mg are clinically equivalent medications. Both contain identical orlistat at the same dose and work exactly the same way in your body. The primary difference is cost: a 4-week supply of generic orlistat costs £29.69 (with EDM10) compared to £38.69 for Xenical. Over 12 weeks, choosing generic orlistat saves £29.70 versus Xenical. Both require a prescription following clinical assessment by a UK-licensed prescriber and are dispensed by our GPhC-registered pharmacy.
Which Orlistat Product Should You Choose?
For most people, generic orlistat 120mg offers the best value while delivering identical clinical results to Xenical. Both products block approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Some patients prefer branded Xenical, while others choose generic orlistat for the cost savings. We also stock Alli 60mg (£26.09 for 4 weeks with EDM10) - the lower-strength alternative for those preferring a gentler starting dose. All three options are available through our online prescription service.
Pack Sizes and Pricing Comparison
Generic orlistat costs: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, 12 weeks (252 capsules) £86.39 - all with EDM10 discount. Xenical costs: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 with EDM10. Taking one capsule three times daily with meals containing fat, most people find 12-week supplies offer the best value for sustained weight management support. Both products work identically regardless of pack size chosen.
How to Get Started
Complete our online health questionnaire for clinical review by a UK-licensed prescriber. Following assessment, your chosen orlistat product will be dispensed by our Leicester-based GPhC-registered pharmacy and delivered discreetly to your address. Use code EDM10 for 10% off every order - whether you choose generic orlistat, Xenical, or Alli. Next day delivery is available across the UK, with prescription included in the price eliminating the need for a separate GP appointment.


