Which Should You Choose: Orlistat or Xenical?
Headaches: Orlistat vs Xenical Comparison
When considering whether orlistat causes headaches, it's important to understand that both generic Orlistat 120mg and branded Xenical 120mg contain the exact same active ingredient at identical doses. Headaches are not listed among the common side effects for either product. The most frequently reported side effects are gastrointestinal, including oily stools and abdominal discomfort, which occur when the medication blocks approximately one third of dietary fat absorption.
If you experience headaches while taking either Orlistat or Xenical, this should be discussed with your prescriber during your clinical assessment or follow-up consultation. Both medications work identically in blocking lipase enzymes in the gut, so any side effect profile differences would be minimal.
Cost Comparison: Why Choose Generic Orlistat?
The primary difference between Orlistat and Xenical is cost, not clinical effectiveness. Generic Orlistat 120mg costs £32.99 for a 4-week supply (84 capsules), reduced to £29.69 with code EDM10. Branded Xenical costs £42.99 for the same 4-week supply, reduced to £38.69 with EDM10. This means choosing generic Orlistat saves you over £9 per month while providing identical clinical benefits.
For longer treatments, the savings increase substantially. A 12-week supply of generic Orlistat costs £86.39 with EDM10, compared to £116.09 for Xenical - a saving of nearly £30. Both options are prescribed following the same online clinical assessment by UK-licensed healthcare professionals.
Alli 60mg: Lower-Strength Alternative
For those concerned about potential side effects including headaches, Alli 60mg provides a lower-strength option. Containing half the dose of prescription-strength orlistat, Alli may be suitable for those preferring a gentler starting point. A 4-week supply costs £28.99, reduced to £26.09 with EDM10. While clinically less potent than 120mg products, Alli still blocks a portion of dietary fat absorption.
Clinical Assessment for Both Options
Whether you choose Orlistat or Xenical, both require prescription following online clinical assessment. Our UK-licensed prescribers review your medical history, current medications, and suitability for orlistat treatment. This includes assessment of any headache history or concerns. The consultation process is identical for both generic and branded options.
Treatment may be suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Both medications must be used alongside a reduced-calorie, lower-fat diet for optimal effectiveness and to minimise gastrointestinal side effects.
Order Process and Delivery
Both Orlistat and Xenical are available through our streamlined process: complete the online health questionnaire, receive prescriber review, and benefit from next day delivery across the UK. All medications are dispensed by our GPhC-registered pharmacy in Leicester with discreet, secure packaging. Remember to use code EDM10 for 10% off your order.


