Which Should You Buy: Generic Orlistat or Xenical?
Orlistat vs Xenical: The Facts
Both orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses. They work by inhibiting lipase enzymes in your gut, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your digestive system. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical.
Price Comparison: Significant Savings with Generic
Generic orlistat offers substantial savings compared to Xenical. A 4-week supply (84 capsules) costs £32.99, or £29.69 with EDM10 discount. Xenical costs £42.99, or £38.69 with EDM10 - a saving of £9 per month choosing generic. For 12 weeks, you save £29.70 with orlistat (£86.39) versus Xenical (£116.09).
Who Chooses Which Option?
Many patients choose generic orlistat for the cost savings, particularly for longer-term treatment. Some prefer branded Xenical from Roche, often due to familiarity with the brand name. Both require the same online clinical assessment by our UK-licensed prescribers and are dispensed by our GPhC-registered pharmacy in Leicester.
Alli 60mg: The Lower-Strength Alternative
Alli contains orlistat at half the prescription dose (60mg). It blocks a smaller proportion of dietary fat and typically causes milder gastrointestinal effects. A 4-week supply costs £28.99 (£26.09 with EDM10). Consider Alli if you prefer starting with a lower-strength option.
How to Order Through EverydayMeds
Complete our online health questionnaire covering your medical history, current medications, and BMI. A UK-licensed prescriber reviews your information and issues a prescription if clinically appropriate. We dispense and dispatch with next-day delivery across the UK. Your prescription is included in the price - no separate GP appointment needed.
Expected Results and Timeline
Orlistat and Xenical may help reduce calorie intake from dietary fat when used alongside a reduced-calorie, lower-fat diet. Keep meals to approximately 15g fat each to minimise side effects. Individual responses vary, and long-term weight management depends on continued dietary and lifestyle changes. Both products work best when combined with regular physical activity.


