Which Orlistat Option Should You Choose?
Orlistat vs Xenical: The Key Differences
Both orlistat 120mg and Xenical 120mg contain identical active ingredients at the same dose. The primary difference is cost. Generic orlistat offers the same clinical effect as branded Xenical but at a lower price point. Orlistat 120mg costs £29.69 for a 4-week supply with code EDM10, whilst Xenical 120mg costs £38.69 for the same period. Both work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Orlistat 120mg: Best Value Option
Generic orlistat 120mg provides excellent value for money without compromising on effectiveness. Available in multiple pack sizes: 42 capsules (2 weeks) for £15.20, 84 capsules (4 weeks) for £29.69, 168 capsules (8 weeks) for £57.59, and 252 capsules (12 weeks) for £86.39 with EDM10. Take one capsule three times daily with each main meal containing fat. Following clinical assessment by our UK-licensed prescribers, orlistat may be suitable for adults with a BMI of 30 or above, or 28 or above with weight-related health conditions.
Xenical 120mg: The Branded Choice
Xenical 120mg by Roche offers the same orlistat formulation in branded packaging. Some patients prefer the assurance of branded medication. Xenical costs £19.35 for 42 capsules, £38.69 for 84 capsules, £78.29 for 168 capsules, and £116.09 for 252 capsules with EDM10. The mechanism of action is identical to generic orlistat, inhibiting lipase enzymes in the gut to reduce dietary fat absorption. Clinical assessment determines suitability on an individual basis.
Alli 60mg: Lower Strength Alternative
Alli 60mg contains half the dose of prescription-strength orlistat. This lower-strength option may be suitable for those preferring a gentler introduction to orlistat treatment. Alli costs £26.09 for 42 capsules (4 weeks), £49.49 for 84 capsules (8 weeks), or £116.99 for 252 capsules (12 weeks) with EDM10. Take one capsule three times daily with meals containing fat. Whilst less potent than 120mg options, Alli may still support weight management when combined with dietary changes.
Making Your Decision: Price vs Preference
Your choice between orlistat, Xenical, or Alli depends on budget and personal preference. Generic orlistat 120mg offers maximum savings, Xenical provides branded reassurance at a premium, and Alli delivers lower-strength introduction. All options require commitment to a reduced-calorie, lower-fat diet for optimal results. Side effects are typically gastrointestinal and can be minimised by limiting fat intake to approximately 15g per meal. Complete our online consultation to determine which option suits your circumstances best.


