Which Should You Choose: Orlistat or Xenical?
Orlistat vs Xenical: Clinical Equivalence
Generic Orlistat 120mg and branded Xenical 120mg contain identical orlistat active ingredient at the same dose. Both work by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat from being absorbed. Clinically, they are equivalent - the key difference lies in price and manufacturer. Orlistat is produced by various generic manufacturers whilst Xenical is made by Roche.
Cost Comparison: Significant Savings with Generic
Generic Orlistat offers substantial savings over branded Xenical. A 4-week supply (84 capsules) costs £29.69 with EDM10 versus £38.69 for Xenical - saving over £9 per month. For a 12-week supply, Orlistat costs £86.39 compared to Xenical's £116.09, representing £30 savings. Both options require the same online prescription process and clinical assessment by UK-licensed prescribers.
Alli 60mg: Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. Available at £26.09 for 4 weeks with EDM10, Alli may suit those preferring a lower-strength starting point or experiencing side effects with 120mg formulations. However, clinical effectiveness is reduced compared to prescription-strength options.
How Both Medications Work
Whether choosing Orlistat or Xenical, the mechanism remains identical. Both must be taken three times daily with main meals containing fat - one 120mg capsule immediately before, during, or up to one hour after eating. When lipase enzymes are blocked, unabsorbed fat passes naturally through the digestive system. This reduction in fat absorption may support weight management when combined with a reduced-calorie, lower-fat diet.
Online Prescription Process
Both Orlistat and Xenical require prescription following clinical assessment. Complete our online health questionnaire covering medical history, current medications, and BMI information. UK-licensed prescribers review applications and issue prescriptions where clinically appropriate. Medications are dispensed by our GPhC-registered pharmacy and delivered with next day tracked service across the UK.
Making Your Choice
Consider generic Orlistat if cost is your primary concern - you'll receive identical clinical benefits at lower price. Choose branded Xenical if you prefer the original manufacturer's product. Both options include the same comprehensive support and delivery service from EverydayMeds. Use code EDM10 at checkout for 10% off your order.


